摘要
肺炎支原体肺炎(MPP)是由肺炎支原体(MP)感染所致的以高发病率、高病死率为特点的呼吸道疾病,多见于儿童和青少年,感染及免疫失衡是目前比较认可的发病机制。近年来,MPP的发病率日益增长,严重威胁儿童的身体健康,因此更新治疗方案是当务之急。维生素D作为一种新的免疫调节剂,具有调控免疫反应及抗感染的功能。目前维生素D在辅助治疗MPP方面已取得了一定的成果,但作用机制尚不明确,通过了解维生素D与MPP之间的关系以及维生素D辅助治疗MPP的作用机制,可以为临床治疗提供帮助。
Mycoplasma pneumoniae pneumonia(MPP)is a respiratory disease caused by Mycoplasma pneumoniae(MP)infection with a high morbidity and mortality,more often seen in children and the adolescent,and infection and immune imbalance are the currently recognized pathogenesis.In recent years,the incidence of MPP is increasing and it is a serious threat to the children′s health,therefore,it is urgent to update the treatment plan.Vitamin D is a new immunomodulator that plays a role in immune regulation and anti-infection.At present,vitamin D has made some achievements in the adjuvant treatment of MPP,but the mechanism is still unclear.It is hoped that the understanding of the relationship between vitamin D and MPP and the action mechanism of vitamin D in the adjuvant treatment of MPP can provide help for the clinical treatment.
作者
张惠敏
熊燚
ZHANG Huimin;XIONG Yi(Department of Pediatrics,Maternal and Child Health Hospital Affiliated to Zunyi Medical University,Zunyi 563000,China)
出处
《医学综述》
2020年第11期2128-2133,2139,共7页
Medical Recapitulate
关键词
肺炎支原体肺炎
维生素D
肺炎支原体
Mycoplasma pneumoniae pneumonia
Vitamin D
Mycoplasma pneumoniae
