摘要
目的探讨多层螺旋CT、MRI联合血清含锰超氧化物歧化酶(Mn-SOD)丙二醛(MDA)诊断肾上腺皮质腺瘤的价值。方法选取2017年4月-2018年3月本院就诊疑似肾上腺皮质腺瘤患者90例,先后进行CT、MRI检查与血清学检查,观察患者影像学联合血清诊断特点以及价值。结果CT检测结果与MRI检测肾上腺疾病类型结果比较差异无统计学意义(P>0.05);肾上腺皮质增生Mn-SOD水平高于皮质腺瘤与嗜铬细胞瘤、MDA水平低于皮质腺瘤与嗜铬细胞瘤(P<0.05);肾上腺皮质腺瘤Mn-SOD水平低于肾上腺嗜铬细胞瘤,MDA水平高于肾上腺嗜铬细胞瘤(P<0.05);多层螺旋CT、MRI联合血清Mn-SOD、MDA诊断肾上腺皮质增生与皮质腺瘤ROC曲线下AUC=0.981高于单独CT扫描AUC=0.849,MRI检查AUC=0.763,MDA诊断AUC=0.907,Mn-SOD诊断AUC=0.901,差异有统计学意义(P<0.05);多层螺旋CT、MRI联合血清Mn-SOD、MDA诊断肾上腺皮质腺瘤与嗜铬细胞瘤ROC曲线下AUC=0.900高于单独CT扫描AUC=0.815,MRI检查AUC=0.711,MDA诊断AUC=0.676,MnSOD诊断AUC=0.717,差异有统计学意义(P<0.05)。结论多层螺旋CT、MRI联合血清Mn-SOD、MDA诊断肾上腺皮质腺瘤效能高于单独检测。
Objective To explore the value of multi-slice spiral CT and MRI combined with serum manganese-containing superoxide dismutase(Mn-SOD) and malondialdehyde(MDA) in the diagnosis of adrenocortical adenoma. Methods A total of 90 patients suspected as adrenocortical adenoma from April 2017 to March 2018 were selected. CT, MRI and serological examination were performed. The diagnosis characteristics and value of imaging combined with serum were observed. Results There was no significant difference between CT detection and MRI detection in the type of adrenal gland diseases(P>0.05). The Mn-SOD level of adrenocorticohyperplasia was higher than that of cortical adenoma and pheochromocytoma while the MDA level was lower than that of cortical adenoma and pheochromocytoma(P<0.05). The Mn-SOD level of adrenocortical adenoma was lower than that of adrenal pheochromocytoma while the MDA level was higher than that of adrenal pheochromocytoma(P<0.05). The AUC(0.981) under ROC curve of multi-slice spiral CT, MRI combined with serum Mn-SOD and MDA was higher than that of CT scan(AUC=0.849), MRI examination(AUC=0.763), MDA diagnosis(AUC=0.907) and Mn-SOD diagnosis(AUC=0.901) in the diagnosis of adrenocorticohyperplasia and cortical adenoma(P<0.05). The AUC(0.900) under ROC curve of multi-slice spiral CT, MRI combined with serum Mn-SOD and MDA was higher than that of CT scan(AUC=0.815), MRI examination(AUC= 0.711), MDA diagnosis(AUC=0.676) and Mn-SOD diagnosis(AUC=0.717) in the diagnosis of adrenal adenoma and pheochromocytoma(P<0.05). Conclusion The efficacy of multi-slice spiral CT, MRI combined with serum Mn-SOD and MDA is higher than that of single detection in the diagnosis of adrenocortical adenoma.
作者
沈美铖
冯旭霞
文铁
SHEN Mei-cheng;FENG Xu-xia;WEN Tie(Department of CT Diagnosis,Affiliated Hospital of Yan'an University,Yan'an 716000,Shaanxi Province,China)
出处
《中国CT和MRI杂志》
2020年第2期102-105,共4页
Chinese Journal of CT and MRI
基金
陕西省社会发展科技攻关项目(No.2016SF-151)。
