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三维重建技术联合腹腔镜肝切除术治疗86例原发性肝癌的临床研究 被引量:12

Clinical study of three dimensional reconstruction combined with laparoscopic hepatectomy in the treatment of 86 primary hepatocellular carcinoma
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摘要 目的分析三维重建技术在腹腔镜肝切除术中的应用效果。方法回顾性分析湖北医药学院附属十堰市太和医院2017年7月至2019年7月收治的86例原发性肝癌患者临床资料。根据是否行三维重建技术将患者分为观察组(n=44)和对照组(n=42),记录并比较两组手术患者的一般情况、手术时间、术中出血量、平均住院时间、术后并发症情况。在术前及术后7 d检测并比较两组患者血清谷丙转氨酶(ALT)、谷草转氨酶(AST)、总胆红素(TBIL)、白蛋白(ALB)和甲胎蛋白(AFP)含量变化。结果观察组手术时间、术中出血量、术后住院时间均优于对照组,差异均具有统计学意义(P<0.05);两组患者术前ALT、AST、TBIL、AFP、ALB含量均无明显差异(P>0.05)。观察组术后7 d ALT、AST、TBIL、AFP含量均低于对照组术后,ALB含量高于对照组术后,且差异均具有统计学意义(P<0.05)。观察组术后并发症较对照组显著降低(P<0.05)。结论三维重建技术应用于腹腔镜肝切除术能够缩短手术时间,减少术中出血量,降低住院时间,改善肝功能,减少术后并发症发生,从而加快患者恢复,确保手术安全,值得在地市级三甲医院推广及应用。 Objective To analyze the clinical application of three-dimensional reconstruction in laparoscopic hepatectomy.Methods A total of 86 patients with primary hepatocellular carcinoma admitted to Taihe Hospital from Jul.2017 to Jul.2019 were analyzed retrospectively.According to whether application of threedimensional reconstruction technology or not,patients were divided into observation group(n=44)and control group(n=42).The general situation,preoperative liver function,operation time,intraoperative hemorrhage,average hospitalization time and postoperative complications were recorded and compared between two groups.The serum levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST),total bilirubin(TBIL),albumin(ALB),and alpha-fetoprotein(AFP)of the two groups were detected and compared before operation and 7 days after operation.Results The operation time,intraoperative hemorrhage and postoperative hospitalization time in the observation group were all superior to those in the control group,and the difference was statistically significant(P<0.05).There were no significant differences in the levels of ALT,AST,TBIL,AFP and ALB between the two groups before operation(P>0.05).The content of ALT,AST,TBIL and AFP in the observation group were lower than those in the control group 7 days after operation,and the ALB content was higher than that in the control group,the difference was statistically significant(P<0.05).The postoperative complication rate in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Three dimensional reconstruction combined with laparoscopic hepatectomy can shorten the operation time,reduce intraoperative bleeding,reduce the length of hospitalization,improve liver function,reduce postoperative complications and speed up the recovery of HCC,which is worthy of promotion and application in prefecture-level hospitals.
作者 卓翔 江斌 ZHUO Xiang;JIANG Bin(Hepatobiliary and Pancreatic Center,Affiliated Taihe Hospital of Hubei University of Medicine,Shiyan,Hubei 442000,China)
出处 《肝胆胰外科杂志》 CAS 2020年第2期84-88,共5页 Journal of Hepatopancreatobiliary Surgery
基金 湖北省卫生健康委科研项目(WJ2019M061)。
关键词 原发性肝癌 三维重建技术 腹腔镜肝切除术 primary hepatocellular carcinoma three-dimensional reconstruction technique laparoscopic liver resection
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