摘要
目的:运用中医传承辅助平台(V2.5)软件,挖掘朱世楷教授治疗慢性萎缩性胃炎的经验及用药规律。方法:收集朱世楷门诊诊断为“慢性萎缩性胃炎”,中医诊断为“胃痛”“痞满”等的病历处方,共139首。借助中医传承辅助平台系统(V2.5)进行用药规律挖掘,主要研究内容包括证型频次、药物频次、性味统计和组方规律分析(用药模式、规则分析、网络展示)等。结果:最常见证型为脾胃气虚证和胃络瘀阻证;补气健脾药和活血软坚药为最常使用的药物;药性以甘温为主,苦寒为辅。最常用药对是活血消癥的莪术、预知子等。13味最常使用药物为炒党参、炒白术、陈皮、茯苓、海螵蛸、白及、莪术、预知子、黄连、干姜、炙甘草、菝葜、炒当归等。结论:朱世楷治疗慢性萎缩性胃炎用药总以扶正健脾益气药为纲,活血祛瘀、软坚散结药为目,均不离其“通”利胃腑,“顺”畅气血的本质,使血脉和利,气血运行无碍,黏膜得新血滋养,则旧疾得去,萎缩渐退,黏膜渐荣。
Objective:To excavate the experience and using drugs regularity of ZHU Shi-kai professor curing chronic atrophic gastritis.Methods:We collected 139 medical prescriptions from ZHU Shi-kai Clinic;the diagnose is"chronic atrophic gastritis",and the diagnose of traditional Chinese medicine are"stomachache,distention and fullness"and so on.With the help with the auxiliary platform for traditional Chinese medicine inheritance(V2.5),we conducted the excavation of using drugs regularity,the main research content contains frequency of syndrome types,frequency of drugs,statistics of sex and taste,and analysis of prescription rules(medication pattern,rule analysis,network display)and so on.Results:The most frequent syndrome types are spleen and stomach Qi deficiency syndrome and stomach collaterals stasis syndrome.Tonifying Qi,invigorating spleen and invigorating blood are the most frequently used drugs,and the drug properties are mainly sweet warm and subsidiarily bitter cold.The most commonly used medicine suits are activating blood circulation elimination of zedoary rhizome(Ezhu),foregone fruit(Yuzhizi)and so on.The were 13 most commonly used drugs,including stir-fry codonopsis pilosula(Chaodanshen),stir-fry atractylodes macrocephala(Chaobaizhu),orange peel(Chenpi),poria(Fuling),sea ladybush(Haipiaoxiao),Bletilla striata(Baiji),zedoary(Ezhu),forerunner(Yuzhizi),rhizoma coptidis(Huanglian),dried ginger(Gnajiang),processed liquorice(Zhingancao),sarsaparilla(Baqia),stir-fry angelica(Chaodangui)and so on.Conclusion:ZHU Shi-kai treats CAG according to strengthening body resistance and spleen Qi for the outline,and promoting blood circulation and removing stasis drugs and so on for the purpose,which aren’t all far from its"tong"stomach,"shun"Qi and blood essence,to make blood circulation and benefit,Qi and blood flow without hindrance,mucosa get new blood nourishing,then old disease go,atrophy gradually retreat,mucosa gradually flourish.
作者
马学慧
朱世楷
沈旦蕾
张征波
MA Xue-hui;ZHU Shi-kai;SHEN Dan-lei;ZHANG Zheng-bo(Wuxi Traditional Chinese Medicine Hospital/Wuxi Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Wuxi Jiangsu 214000,China)
出处
《中医药导报》
2019年第23期48-52,共5页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
2017无锡市卫计委重大科技项目（Z201715）
关键词
数据挖掘
慢性萎缩性胃炎
用药规律
朱世楷
通顺疗法
data exploring
chronic atrophic gastritis
drug rules
ZHU Shi-kai
Tongshun therapy
