摘要
该文对我国过去10年来艾滋病流行出现的新变化新特点进行简要概述。当前我国艾滋病流行形势总体平稳,但地区差异显著。男男同性性行为者、老年男性人群中HIV感染风险较高,HIV基因亚型更加复杂,CRF01_AE、CRF07_BC、CRF08_BC的流行率不断上升,抗逆转录病毒治疗覆盖率显著提高,治疗效果显著,但未接受过抗病毒治疗的HIV感染者中原发性耐药率也显著增加。为应对我国艾滋病流行呈现出的新特点,需要适时调整艾滋病防控策略。
This review is intended to provide an overview of newly occurred changes and characteristics of the HIV epidemic over the past decade in China. Both domestic and international literature about HIV epidemic in China in the past ten years were searched and reviewed to provide a brief summary of current status of the HIV epidemic,profiles of HIV risks among key populations,genetic subtypes,and drug resistance,as well as coverage and effectiveness of antiretroviral therapy( ART).The recent HIV epidemic has been stable overall in China,though there are substantial geographic variations. Men who have sex with men( MSM),older men are at high or increasing risks of HIV infection. Various HIV subtypes or recombinant forms have been identified,with CRF01_AE,CRF07_BC and CRF08_BC increasingly popularized. The national ART program has been drastically scaled up and effective,with cautions on escalated transmission of HIV drug resistance among ART-naive patients. The recent HIV epidemic in China presents new changes and characteristics, underscoring needs of strategic adjustment for HIV control and prevention.
作者
何纳
HE Na(School of Public Health,Hehai University,Shanghai 200032,China)
出处
《上海预防医学》
CAS
2019年第12期963-967,共5页
Shanghai Journal of Preventive Medicine
基金
国家自然科学基金课题(81773485)
上海市卫生健康委课题(GWTD2015S05)
国家传染病防治科技重大专项课题(2018ZX10721102-004)
关键词
艾滋病
高危人群
监测
分子流行病学
抗病毒治疗
HIV/AIDS
high risk groups
surveillance
molecular epidemiology
antiretroviral therapy
