摘要
目的评价合肥某医院妇产科门诊患者的HPV感染情况.方法采集2018年妇产科门诊6912例患者的宫颈脱落细胞,提取DNA,检测HPV基因型,分析患者感染率及亚型.结果6912例的女性患者标本,检出2627例HPV阳性患者,总阳性率为38.0%.高危型HPV52感染率8.0%为最高,≥56岁组的总阳性率和高危型感染率最高,为53.02%和50.48%,26~35岁组总阳性率和高危型感染率最低,为33.09%和29.96%.随着感染型别的个数增加各分组的感染率减少,最高的单一感染总计1782例(25.78%),最低的多重感染236例(3.41%).结论研究该院门诊患者HPV分布有年龄和型别的差异,患者感染以高危型、单一感染为主,针对该地区HPV疫苗接种的选择提供很好的理论支持.
Objective To analyze the infection status of human papillomavirus(HPV)in outpatient department of obstetrics and gynecology of a hospital in Hefei.Methods The cervical exfoliated cells were collected from 6912 obstetrics and gynecology outpatient patients in 2018,DNA was extracted,HPV genotypes were detected,and infection rates and subtypes were analyzed.Results 2627 were found to be HPV positive from 6912 female patients,with a total positive rate of 38.0%.Among them,the high-risk HPV52 infection rate was 8.0%,the total positive rate and high-risk infection rate were 53.02%and 50.48%in the group of 56 years old above,and the total positive rate and high-risk infection rate were 33.09%and 29.96%respectively in the group 26~35 years old.As the number of infection types increased,the infection rate of each group decreased.The rate of single infection was the highest,it was 1782 cases(25.78%),that is,and the rate of multiple infection was the lowest,it was 236 cases(3.41%),Conclusion There are different e distributions of HPV in outpatients of this hospital in type and age,and the infection is mainly high-risk type and single infection,which provides good theoretical support for the selection of HPV vaccination in this region.
作者
周猷伟
李绪清
王彦
程玲慧
李洪言
ZHOU You-wei;LI Xu-qing;WANG Yan(The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui 230032)
出处
《临床输血与检验》
CAS
2019年第6期596-599,共4页
Journal of Clinical Transfusion and Laboratory Medicine
基金
安徽省高校科学研究重点项目(No.KJ2018-A018)资助
