摘要
Objective:To analyze the features and patterns of acupoint selection in acupuncture-moxibustion treatment of chronic atrophic gastritis(CAG)by data mining technique.Methods:Relevant clinical studies published before 25 June,2017 were searched in databases including PubMed,EMBASE,Cochrane library,Chinese Biomedical Literature Database(CBM),China National Knowledge infrastructure(CNKI),and Wanfang Academic Journal Full-text Database(Wanfang).Results:A total of 122 papers were included,involving 69 points.It was found that the top three points on the frequency list were Zusanli(ST 36),Zhongwan(CV 12)and Weishu(BL 21).The points selected were distributed in 11 meridians,in which the Stomach Meridian of Foot Yangming,Conception Vessel,and Bladder Meridian of Foot Taiyang ranked the top and accounted for 74.0%of the total frequency.Of the involved specific points,Five Shu-Transmitting points,crossing points and Back-Shu points ranked the top,accounting for 47.1%.The analysis of association pattern has shown that Zusanli(ST 36)and Zhongwan(CV 12)won the highest support rate in the paired groups;Zusanli(ST 36),Weishu(BL 21)and Zhongwan(CV 12)had the highest support rate among the point groups.The Five Shu-Transmitting points and the Lower He-Sea points had the highest support rate among the specific point groups.Conclusion:The data mining results of the studies on acupuncture-moxibustion for CAG are substantially in line with the acupuncture-moxibustion treatment theories in traditional Chinese medicine.The results can reflect the acupoint selection patterns in treatment of CAG and provide reference for acupuncture-moxibustion treatment of CAG in clinic.
目的:通过数据挖掘方法分析针灸治疗慢性萎缩性胃炎(CAG)的选穴特点及规律。方法:收集整理PubMed、EMBASE、Cochrane library、医学文献数据库(CBM)、中国知网(CNKI)和万方数据库(Wanfang)2017年6月25日前发表的相关临床文献,建立针灸临床处方数据库。结果:共纳入文献122篇,涉及69个穴位。针灸治疗CAG所选穴位频次位居前三位为足三里、中脘、胃侖。所选穴位分布在11条经络。所选经脉频次前三位为足阳明胃经、任脉及足太阳膀胱经,共占总频次的74.0%。所选特定穴频次前三位的为五输穴、交会穴及背俞穴,共占总频次的47.1%。关联规则分析显示穴对配伍支持度最高的为足三里和中脘;穴组支持度最高的为足三里和胃俞配中脘;特定穴配伍支持度最高的为下合穴和五输穴。结论:针灸治疗CAG文献的数据挖掘结果与传统中医学中针灸治疗理论基本相符,能够反映出CAG的临床选穴组合规律,可为临床针灸治疗CAG提供参考。
作者
Li Zhi-xing
Huang Run-ze
Zhang Hai-hua
Chen Xiao-zhuan
Lin Bao-cheng
Hu Cheng-xiang
Huang De-yu
李知行;黄润泽;张海华;陈小砖;林宝城;胡成想;黄德裕(Department of Soft Tissue Traumatology,Fourth Affiliated Hospital of Guangzhou University of Chinese Medicine,Shenzhen 518033,China;Department of Endocrinology,the First Affiliated Hospital of Guangdong Pharmaceutical University,Guangzhou 510080,China;Department of Massage,the Fourth Affiliated Hospital of Guangzhou University of Chinese Medicine,Shenzhen,518033,China;Artemisia Annua Research Center,Guangzhou University of Chinese Medicine,Guangzhou 510405,China)
基金
国家自然科学基金面上项目,No.81473756,No.81804167
深圳市卫生计生系统科研项目博士创新项目,No.SZBC2017025。
