摘要
目的调查宫颈癌放疗患者的生活质量及其影响因素。方法本研究纳入2013年12月至2018年12月北京协和医院诊治的205例宫颈癌患者。采用宫颈癌生活质量评估量表(FACT-CxV4. 0)中文版对患者生活质量进行评估,同时收集患者人口学资料,包括年龄、文化程度、婚姻状况、家庭状况和职业等;治疗资料包括临床分期和治疗方式等,采用Mann-Whitney U检验及Kruskal-Wallis检验等统计学方法,分析各因素对宫颈癌患者生活质量的影响。结果纳入研究的宫颈癌放疗患者生活质量总分为109(93,123)分,其中生理状况为18(15,21)分;社会/家庭状况为20(17,23)分;情感状况为18(16,20)分;功能状况为16(11,21)分;附加关注为37(32,42)分。年龄(P<0. 05)、放疗是否结束(P<0. 01)、家庭状况(P<0. 01)和婚姻状况(P<0. 01)是影响宫颈癌放疗患者生活质量的因素。结论宫颈癌放疗患者的生活质量受多种因素影响,应积极处理放疗相关并发症,加强患者教育及康复指导,以提高患者生活质量。
Objective To investigate the quality of life and its influencing factors incervical cancer patients undergoing radiotherapy. Methods This study included 205 patients with cervical cancer diagnosed and treated by Peking Union Medical College Hospital from December 2013 to December 2018. The Clinical Assessment of Cancer Therapy-Cervix V4.0 (FACT-Cx V4) was used to assess the quality of life of patients, and collect demographic data including age, education, marital status, family status, occupation, etc.;treatment data including clinical stage, treatment, etc., using Mann-Whitney U test and Kruskal -Wallis test and other statistical methods to analyze the impact of various factors on the quality of life of patients with cervical cancer. Results The total quality of life of patients with cervical cancer who were included in the study was 109(93,123), including 18(15,21) for physical status, 20(17,23) for social/family status,18(16,20)for emotional status, 16(11,21) for functional status, 37(32,42) for additional attention.Age ( P <0.05), end of radiotherapy ( P <0.01), family status ( P <0.01) and marital status ( P <0.01) were factors influencing the quality of life of patients with cervical cancer undergoing radiotherapy. Conclusions The quality of life of patients with cervical cancer undergoing radiotherapy is affected by many factors. The complications related to radiotherapy should be actively treated, and the education and rehabilita- tion guidance should be strengthened to improve the quality of life of patients.
作者
甄宏楠
田园
沈晶
马佳彬
王文惠
管慧
张福泉
ZHEN Hong-nan;TIAN Yuan;SHEN Jing;MA Jia-bin;WANG Wen-hui;GUAN Hui;ZHANG Fu-quan(Department of Radiation Oncology,Peking Union Medical Colledge Hospital,CAMS & PUMC,Beijing 100730,China;Department of Anesthesiology,Peking Union Medical Colledge Hospital,CAMS & PUMC,Beijing 100730,China)
出处
《基础医学与临床》
CSCD
2019年第11期1618-1622,共5页
Basic and Clinical Medicine
关键词
宫颈癌
放疗
生活质量分析
cervical cancer
radiotherapy
quality of life analysis
