摘要
目的:探讨自身免疫性溶血性贫血对ABO血型鉴定及交叉配血结果的影响。方法:收集2016年2月至2018年11月来江西省新余市妇幼保健院进行治疗的50例自身免疫性溶血性贫血患者的临床资料。其中男性30例,女性20例;年龄为3~50岁,平均年龄为(20.77±7.66)岁。观察抗人球蛋白试验结果和血型鉴定及交叉配血结果。结果:50例患者的DAT均为阳性,IAT均为阳性;抗体类型以温抗体为主。随着DAT阳性强度升高,ABO血型正反定型血型相符率和交叉配血相合率逐渐下降(P <0.05);不同抗体类型患者ABO血型正反定型血型相符率和交叉配血相合率的差异无统计学意义(P> 0.05)。结论:自身免疫性溶血性贫血患者以温抗体型为主,DAT强度与血型不符及交叉配血不合有一定的联系。
Objective: To investigate the influence of autoimmune hemolytic anemia on ABO blood group identification and cross matching results. Methods: The clinical data of 50 patients with autoimmune hemolytic anemia treated in Maternal and Child Health Hospital of Xinyu, Jiangxi from February 2016 to November 2018 were collected. Among them there were 30 males and 20 females;the age ranged from 3 to 50 years, and the average age was(20.77±7.66) years old. The results of antihuman globulin test, blood group identification and cross matching results were observed. Results: The results of 50 patients showed that DAT was positive, IAT was positive;temperature antibody was the main type of antibody. With the increase of DAT positive intensity, the compatibility rates of positive and negative ABO blood group typing and cross matching decreased gradually(P<0.05);there was no statistical difference in the compatibility rates of positive and negative ABO blood group typing and cross matching among patients with different antibody types(P>0.05). Conclusion: Temperature antibody is the main type in patients with autoimmune hemolytic anemia, and there is a certain relationship between DAT intensity and blood group inconsistency and cross matching inconsistency.
作者
林水庚
张春根
欧阳娜
LIN Shuigeng;ZHANG Chungen;OUYANG Na(Department of Blood Transfusion of Maternal and Child Health Hospital of Xinyu, Jiangxi 338025, China;Department of Rehabilitation of Maternal and Child Health Hospital of Xinyu, Jiangxi 338025, China)
出处
《上海医药》
CAS
2019年第18期39-41,共3页
Shanghai Medical & Pharmaceutical Journal