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磁共振微血管侵犯征象预测孤立性肝癌术后早期复发的研究 被引量:3

Microvascular invasion features on MRI predicts the early relapse of solitary large hepatocellular carcinoma
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摘要 目的 探讨磁共振微血管侵犯(MVI)征象与孤立性肝癌术后早期复发的相关性,并评估其预测价值。方法分析绵阳市中心医院87例孤立性肝癌患者的磁共振资料,患者均行根治性切除术并进行术后随访。将磁共振MVI与手术病理结果及术后随访结果进行对照分析。结果磁共振MVI征象预测病理MVI的敏感度为84.21%(32/38),特异度为85.71%(42/49),准确度分别为85.06%(74/87),约登指数为0.70。磁共振MVI征象与手术病理MVI结果存在相关性(r=0.744)。磁共振MVI征象预测术后早期复发的敏感度为77.14%(27/35),特异度为76.92%(40/52),准确度为77.01%(67/87),约登指数为0.54。磁共振MVI征象与早期复发存在相关性(r=0.674)。结论磁共振MVI征象对孤立性肝癌术后早期复发有一定的预测价值,可为临床孤立性肝癌制定治疗方案提供参考。 Objective To investigate the correlation between the features of microvascular invasion (MVI) on MRI and early recurrence of solitary large hepatocellular carcinoma (SLHCC) after operation.Methods The clinical data of 87 patients with SLHCC who received radical excision and postoperative follow-up were analyzed.Early recurrence (2 years) was the end point of follow-up.The features of MVI on MRI were matched with the results of surgical pathology and follow-up.Results The sensitivity, specificity and accuracy of MR MVI features in predicting pathological MVI were 84.21%(32/38),85.71%(42/49), 85.06%(74/87) respectively.And Youden index was 0.70.The features of MVI were correlated with the results of surgical pathology ( r = 0.744).The sensitivity, specificity,accuracy and Yoden index of MR MVI in predicting early recurrence were 77.14%(27/35),76.92%(40/52),77.01%(67/87) and 0.54 respectively.MVI features on MRI were correlated with early recurrence ( r = 0.674).Conclusions MVI features on MRI has predictive value for early recurrence of SLHCC,which provides reference for clinical treatment for SLHCC.
作者 王忠 周莹 刘启榆 杨伟 周西 范丹丹 WANG Zhong;ZHOU Ying;LIU Qiyu;YANG Wei;ZHOU Xi;FAN Dandan.(Department of Radiology,Center Hospital of Mianyang,Mianyang 621000,China)
出处 《中国肿瘤外科杂志》 CAS 2019年第4期274-277,共4页 Chinese Journal of Surgical Oncology
关键词 孤立性肝癌 磁共振微血管侵犯征象 术后早期复发 Solitary hepatocellular carcinoma MRIfeatures of microvascular invasion Early recurrence
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