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联用氯吡格雷和阿司匹林治疗心肌梗死的临床疗效及不良反应探讨

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摘要 目的探讨联用氯吡格雷和阿司匹林治疗心肌梗死的临床疗效及不良反应。方法选择2016年6月至2017年9月心肌梗死患者90例根据治疗方法分组。对照组给予单一阿司匹林治疗,观察组则给予阿司匹林联合氯吡格雷治疗。比较两组心肌梗死临床治疗效果;平均住院时间;治疗前后患者左心射血分数、血浆黏度、血小板计数、部分活化凝血活酶时间;药物不良反应率。结果观察组心肌梗死临床治疗效果高于对照组,P<0.05;观察组平均住院时间短于对照组,P<0.05;治疗前两组左心射血分数、血浆黏度、血小板计数、部分活化凝血活酶时间相近,P>0.05;治疗后观察组左心射血分数、血浆黏度、血小板计数、部分活化凝血活酶时间优于对照组,P<0.05。观察组药物不良反应率和对照组无明显差异,P>0.05。结论阿司匹林联合氯吡格雷治疗心肌梗死的应用效果确切,可有效改善血小板聚集情况和心功能,缩短疗程,且无严重不良反应,安全有效,值得推广应用。
作者 吕娜
机构地区 丹东市第一医院
出处 《中国医药指南》 2019年第23期112-113,共2页 Guide of China Medicine
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