摘要
目的:比较阴茎勃起不同时相的海绵体动脉血流动力学,确定阴茎彩色多普勒超声检测的最佳时相。方法:对40例勃起功能正常的健康成年志愿者,以前列地尔注射液10μg进行阴茎海绵体内注射,同时给予视听觉刺激,之后30 min,动态监测双侧阴茎海绵体动脉血流,分别检测充盈期、胀大期、完全勃起期、坚挺期的收缩期峰值流速(PSV)、舒张末期流速(EDV)、阻力指数(RI),比较4个时相的PSV、EDV及RI。结果:40例受检者中14例只经历充盈期、胀大期、完全勃起期,未进入坚挺期。胀大期及完全勃起期PSV、RI均显著高于充盈期(P<0.01),EDV均显著低于充盈期(P<0.01);完全勃起期与胀大期PSV比较,无显著性差异(P>0.05);完全勃起期与胀大期EDV、RI比较,差异均具有统计学意义(P<0.01)。26例达到坚挺期者完全勃起期与坚挺期比较PSV、EDV、RI,均具有显著性差异(P<0.01)。同一时相左右两侧比较,差异均无统计学意义(P>0.05)。结论:阴茎勃起过程中海绵体动脉血流呈现动态变化,在完全勃起期检测出的血流结果能更真实反映阴茎海绵体血管功能。
Objective: To compare the hemodynamic indexes of penile cavernosal arteries in different phases of penile erection and determine the optimal time for color Doppler ultrasonography of the penis. Methods: Forty healthy adult male volunteers with normal erectile function received intracavernous injection of 10 μg Alprostadil together with visual and auditory stimuli. Within the next 30 minutes, we monitored dynamically the blood flow in the bilateral penile cavernosal arteries, and recorded and compared the peak systolic velocity(PSV), end diastolic velocity(EDV) and resistance index(RI) in the phases of latency, tumescence, full erection and rigid erection. Results: Fourteen of the subjects experienced latency, tumescence and full erection only, but failed to achieve rigid erection. PSV and RI were significantly higher while EDV remarkably lower in the tumescence and full erection phases than in the latency phase(all P < 0.01). Statistically significant differences were observed between the tumescence and full erection phases in EDV and RI(both P < 0.01) but not in PSV(P > 0.05). Among the 26 males that achieved rigid erection, PSV, EDV and RI showed significant differences between the full and rigid erection phases(all P < 0.01), but not between the left and right cavernosal arteries in the same phase(P > 0.05). Conclusion: The blood flow in the penile cavernosal arteries changes dynamically in the process of penile erection, and the hemodynamic indexes obtained in the full erection phase can better reflect the function of penile cavernous vessels.
作者
孙国海
汪珣
韩友峰
闻宝杰
戴玉田
石亮
SUN Guo-hai;WANG Xun;HAN You-feng;WEN Bao-jie;DAI Yu-tian;SHI Liang(Department of Urology and Andrology ,Drum Tower Hospital Affiliated to Nanjing University School of Medicine, Nanjing, Jiangsu 210008 , China;Department of Diagnostic Ultrasound, Drum Tower Hospital Affiliated to Nanjing University School of Medicine, Nanjing, Jiangsu 210008 , China)
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2019年第7期608-612,共5页
National Journal of Andrology
