摘要
目的:观察肺炎支原体肺炎(MPP)患儿胸片改变为节段性肺炎或支气管肺炎时的年龄、发热时间、外周血WBC、血清C反应蛋白(CRP)及血清肺炎支原体抗体(MP-IgG)滴度变化情况。方法:我院收治的219例MPP患儿根据胸片改变情况分为节段性肺炎组和支气管肺炎组,检测两组患儿外周血WBC、CRP及MP-IgG滴度指标。结果:219例MPP患儿中,节段性肺炎组65例(29.6%),平均年龄(93.98±14.57)月,支气管肺炎组154例(70.4%),平均年龄(54.73±16.43)月(P<0.05);入组时平均发热时间节段性肺炎组(3.52±1.48) d,支气管肺炎组(2.51±0.99) d(P<0.05);节段性肺炎组血清MP-IgG≥1∶640的例数多于支气管肺炎组(P<0.05);节段性肺炎组血清CRP高于支气管肺炎组(P<0.05)。结论:MP感染后肺部炎症表现为节段性肺炎的患儿年龄偏大、发热时间较长、血CRP水平和MP-IgG滴度更高,提示患儿全身炎症反应强烈,年长儿童MP感染后易发生严重肺部病变。
Objective: To observe the changes of age,fever time,peripheral blood WBC,serum C-reactive protein( CRP) and serum Mycoplasma pneumoniae antibody titer( MP-IgG) in children with Mycoplasma pneumoniae pneumonia( MPP) when the chest radiograph was changed to segmental pneumonia or bronchopneumonia.Methods: A total of 219 children with MPP were divided into the segmental pneumonia group and the bronchopneumonia group according to the changes of chest radiograph.Meanwhile,WBC,CRP and MP-IgG titers were measured in both groups.Results: Of the 219 children with MPP,65 cases( 29.6%) were in the segmental pneumonia group with an average age of( 93.98±14.57) months,and 154 cases( 70.4%) were in the bronchopneumonia group with an average age of( 54.73±16.43) months( P<0.05).The mean fever time was( 3.52±1.48) d in the segmental pneumonia group,and( 2.51±0.99) d in the bronchopneumonia group( P<0.05),the number of cases in the segmental pneumonia group with serum MP-IgG≥1 ∶ 640 was larger than that in the bronchopneumonia group( P<0.05).The serum CRP value of the segmental pneumonia group was higher than that of the bronchial pneumonia group( P<0.05).Conclusion: Pulmonary inflammation after MP infection was manifested as segmental pneumonia in children with older age,longer fever time,higher CRP levels and MP-IgG titer.It is suggested that the systemic inflammatory response is strong in children,and elderly children are prone to severe lung disease after MP infection.
作者
温晓滨
刘丽
陶蜀杭
向玲
Wen Xiaobin;Liu Li;Tao Shuhang;Xiang Ling(The Second People's Hospital of Chengdu, Sichuan Chengdu 610014, China)
出处
《儿科药学杂志》
CAS
2019年第7期1-3,共3页
Journal of Pediatric Pharmacy
关键词
肺炎支原体
抗体
节段性肺炎
C反应蛋白
儿童
Mycoplasma pneumoniae
antibody
segmental pneumonia
C-reactive protein
children
