摘要
酒精成瘾作为一种慢性高复发性的疾病,严重影响个人健康并导致相关社会问题。但目前对酒精成瘾的治疗仍缺少降低渴求、预防复发的有效方法。重复经颅磁刺激是目前成瘾领域逐渐兴起的一种干预手段,本文综述了其在酒精成瘾领域的相关研究,介绍了经颅磁刺激的工作原理及其对酒精依赖者相关脑区功能及神经递质的影响。已有研究显示重复经颅磁刺激对于降低酒精渴求有一定效果,但现有研究方案及其结果不尽相同,最佳治疗方案有待明确。在今后的研究中,可以尝试探索优化治疗方案,增加生物学疗效指标,为进一步推广临床应用提供更多证据。
Alcohol dependence as a chronic disease with high relapse rates, seriously affects individual health and causes related social problems. However, the treatment of alcohol addiction currently lacks effective interventions to reduce craving and prevent relapse. Repetitive transcranial magnetic stimulation (rTMS) is an emerging intervention in the field of addiction. This paper reviews the researches to introduce the working principle of TMS and its effects on brain functions and neurotransmitters of alcohol dependent patients. Studies have shown that rTMS has a certain effect on reducing alcohol craving, but the existing research protocols and their results are not exactly same, and the best parameters need to be clarified. Future research can try to explore optimized treatment options, and find biological efficacy indicators to provide more evidence for further clinical application.
作者
袁辰馨
任其欢
苏杭
杜江
Yuan Chenxin;Ren Qihuan;Su Hang;Du Jiang(Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China;Hongkou District Shanghai Mental Health Center, Shanghai 200083, China)
出处
《中华行为医学与脑科学杂志》
CAS
CSCD
北大核心
2019年第6期563-567,共5页
Chinese Journal of Behavioral Medicine and Brain Science
基金
国家自然科学基金项目(81871045)
上海市卫生和计划生育委员会(精神病学)重点学科(2017ZZ02021)
虹口区"临床医学优秀青年人才"培养计划(HKYQ2018-18).
关键词
重复经颅磁刺激
酒精成瘾
干预
Repetitive transcranial magnetic stimulation
Alcohol addiction
Intervention Contributor Information
