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CT引导下氩氦刀治疗晚期肾肿瘤的临床疗效及安全性观察

Clinical efficacy and safety of CT-guided argon-helium cryoablation for advanced renal tumors
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摘要 目的:观察CT引导下氩氦刀治疗晚期肾肿瘤的疗效及安全性。方法:抽取晚期肾肿瘤患者32例为研究对象,对所有患者行CT引导下氩氦刀治疗,观察近期、远期疗效及并发症发生率。结果:治疗1个月后,13例病灶缩小,19例病灶无明显变化;治疗1年后,22例部分缓解,6例病情稳定,治疗总有效率为87.50%;患者术后3dBUN(3.95±0.98)mmol/L、Scr(47.65±12.33)μmol/L与术前(4.14±1.04)mmol/L、(45.37±13.26)μmol/L比较,差异无统计学意义(P>0.05);围手术期中8例出现一过性高血压、腹膜后局限性出血、局部酸痛、发热等不良反应,发生率为25.00%。结论:CT引导下氩氦刀治疗晚期肾肿瘤近远期疗效确切,且安全性高。 Objective: To observe efficacy and safety of CT-guided argon-helium cryoablation in patients with advanced renal tumors. Methods: 32 patients with advanced renal tumors were selected as the study objects. All patients underwent CT-guided argon-helium cryoablation. The short-term and long-term effects and complications were observed. Results:(1) 1 month after the treatment, the lesions in 13 cases were reduced, and the lesions in 19 cases showed no significant changes.(2) 1 year after the treatment, 22 patients were partially relieved, 6 patients were stable, and the total effective rate was 87.50%.(3) There were no statistical differences in the BUN (4.14±1.04 vs. 3.95±0.98 mmol/L) and Scr (45.37±13.26 vs. 47.65±12.33μmol/) levels before and 3 days after the treatment (P>0.05).(4) During the perioperative period, the complications occurred in 8 cases with a incidence rate of 25.00%, including transient hypertension, post-peritoneal localized hemorrhage, local pain, fever and other adverse reactions. Conclusions: CT-guided argon-helium cryoablation is effective and safe in the treatment of advanced renal tumors with definite short-term and longterm effects.
作者 王晓冰 WANG Xiaobing(Anyang Tumor Hospital, Anyang 455000 Henan, China)
机构地区 安阳市肿瘤医院
出处 《中国民康医学》 2019年第10期6-7,10,共3页 Medical Journal of Chinese People’s Health
关键词 肾肿瘤晚期 CT 氩氦刀 临床疗效 安全性 Advanced Renal tumor CT Argon-helium cryoablation Clinical efficacy Safety
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