摘要
目的探讨改良肺康复训练计划在中度以上慢性阻塞性肺疾病(COPD)患者中的应用效果.方法将2016年7月~2018年7月合肥医学院第五附属(珠海)医院收治的80例中度以上COPD患者按就诊顺序分为研究组(41例)和参照组(39例).参照组给予常规治疗护理措施+呼吸训练,研究组在参照组基础上给予改良肺康复训练计划,两组均干预12周.比较两组干预前后的6min步行试验(6MWT)距离、改良版英国医学研究委员会呼吸问卷(mMRC)评分、圣乔治呼吸问卷(SGRQ)评分、血清白细胞介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)水平.结果干预前,两组的6MWT距离、mMRC评分、SGRQ评分、IL-6和TNF-α水平比较,差异均无统计学意义(P>0.05).干预后,研究组的6MWT距离明显大于参照组,mMRC和SGRQ评分明显低于参照组(P<0.05);研究组的IL-6、TNF-α水平明显低于参照组(均P<0.05).结论改良肺康复训练计划应用于中度以上COPD患者,可以有效提高其运动耐力,缓解其呼吸困难症状,改善其生活质量和炎症反应.
Objective To explore the effect of improved pulmonary rehal)ilitation training program in patients with above moderate chronic obstructive pulmonary disease (COPD). Methods All of 80 patients with above moderate COPD admitted to the Fifth Affiliated (Zhuhai) Hospital of Zunyi Medical College from July 2016 to July 2018 were divided into the study group (41 cases) and reference group (39 cases) according to the order of treatment. The reference group was given routine treatment and nursing measures + breathing training, and the study group was given a modified pulmonary rehabilitation training program based on the referenee group. Both groups were treated for 12 weeks. The distance of 6-minute walk test (6MWT), improved British Medical Research Council Respiratory Questionnaire (mMRC) score, St.George's Respiratory Questionnaire (SGRQ) score, serum interleu kin-6 (IL-6) and tumor necrosis factor-α(TNF-α) levels were compared between the two groups before and after intervention. Results There were no significant differences in the distance of 6MWT, mMRC score, SGRQ score,IL-6 and TNF-α levels between the two groups before intervention (P>0.05). After intervention, the distance of 6MWT of the study group was significantly larger than the reference group, and the mMRC and SGRQ scores were significantly lower than the reference group (P<0.05). The levels of IL-6 and TNF-a in the study group were significantly lower than those in the reference group (P<0.05). Conclusion Applying the improved pulmonary rehabilitation training program in patients with moderate or above COPD can effectively improve their exercise tolerance, relieve symptoms of dyspnea, improve quality of life and inflammatory response of patients.
作者
胡丙兰
肖金红
赖筱珊
周玲燕
曾美琼
HU Bing-lari;XIAO Jin-hong;LAI Xiao-shan;ZHOU Ling-yan;ZENG Mei-qiong(Department of Respiratory Medicine, the Fifth Affiliated (Zhuhai) Hospital of Zunyi Medical College, Guizhou Province,Zunyi 519100, China)
出处
《中国当代医药》
2019年第15期213-215,共3页
China Modern Medicine
关键词
中度以上COPD
改良肺康复训练
运动耐力
生活质量
Chronic obstructive pulmonary disease above moderate
Improved pulmonary rehabilitation training
Exercise endurance
Quality of life
