摘要
目的总结胸腹联体婴的治疗经验,探讨联体婴儿的术前评估要点及治疗策略。方法回顾2009—2016年广州市妇女儿童医疗中心收治的4例胸腹联体婴儿的临床资料,分析影像学评估策略,并发畸形对手术时机的影响,手术分离技巧以及胸腹联体婴儿诊治流程。结果联体婴儿男童2例,女童2例,入院后均接受全面评估,4例均诊断为胸腹联体畸形。4例联体儿体桥内均可见肝脏相连,但有各自独立肝门、胆管及胆囊;胃肠道系统、泌尿系统完全独立无异常;均合并严重的先天性心脏畸形。1例因共用单个四腔心脏,放弃治疗后死亡;其余3例因循环不稳定导致肺炎,符合提前行分离手术指征,经多学科会诊后制定治疗方案;应用带蒂皮瓣转移联合补片方法修补体桥分离后的腹壁缺损,手术平均年龄为(35±6)d。成功分离6名个体,4名患儿术后出现伤口愈合不良,1名患儿于分离术后25d行心脏畸形矫治术,平均住院时间(79±9)d。随访6个月至9年,1名于出院后半年因心脏畸形并发症死亡,其余5名患儿存活。结论通过对胸腹联体婴进行全面评估,多学科协作,严格掌握手术提前和急诊手术指征,制定精细体桥分离方案和序贯治疗并发畸形,可提高胸腹联体婴双胎存活率。
Objective To summarize the experiences of treating thoracoabdominal conjoined infants and discuss the preoperative evaluations and treatment strategies of conjoined infants.Methods The clinical data of 4 hospitalized cases of thoracoabdominal conjoined infants from 2009 to 2016 were reviewed.The imaging evaluation strategy,influence of complicated malformation on operative opportunity,surgical separation techniques and diagnosis and treatment process of thoracoabdominal conjoined infants were analyzed.Results There were 2 male and 2 female conjoined babies.All of them were evaluated after admission.All four cases were all diagnosed as thoracoabdominal conjoined deformity.Liver connections in body bridges were independent of hepatic portal,bile duct and gallbladder.And gastrointestinal tract system and urinary tract were completely independent and showed no abnormalities.All of them were combined with severe congenital heart malformations.One case died after giving up treatment because of sharing a single four-chamber heart.Another 3 cases had pneumonia due to unstable circulation and fulfilled the indication of early separation.Treatment plan was formulated after multi-disciplinary(MDT)consultation.Abdominal wall defect was repaired after body bridge separation by pedicle flap transfer plus patching.The mean operative age was(35±6)days.Six patients were successfully separated and 4 children had poor wound healing after operation.One patient underwent cardiac deformity correction at 25 days after separation.The average hospitalization time was(79±9)days.One patient died of complications of cardiac malformation and another 5 children survived during a follow-up period of 6-9 years after discharge.Conclusion The survival rate of thoracoabdominal conjoined twins may be improved by comprehensive evaluations of thoracoabdominal conjoined infants,multidisciplinary cooperation,strict grasp of early and emergency surgical indications,establishment of fine body-bridge separation scheme and sequential treatment of concomitant malformations.
作者
颜斌
余家康
钟微
何秋明
王哲
李莎
Yan Bin;Yu Jiakang;Zhong Wei;He Qiuming;Wang Zhe;Li Sha(Department of Neonatal Surgery,Guangzhou Women & Children's Medical Center,Guangzhou Medical University,Guangzhou 510623,China)
出处
《临床小儿外科杂志》
CAS
2019年第4期304-309,314,共7页
Journal of Clinical Pediatric Surgery
基金
广东省科技计划项目(编号:2014A020212022)
