摘要
目的比较单纯修补术和胃大部分切除术治疗急性胃穿孔的临床效果。方法选取2017年5月至2018年4月本院收治的66例急性胃穿孔患者为研究对象,采用计算机随机分组法将其分为对照组与研究组,各33例。对照组采用胃大部分切除术,研究组采用单纯修补术。比较两组的治疗效果。结果研究组的治疗总有效率高于对照组(P<0.05)。研究组的术中出血量少于对照组,手术时间、首次排气时间、术后下床时间及住院时间均短于对照组,术后2、24 h疼痛评分低于对照组(P<0.05)。研究组的C反应蛋白、IL-6、IL-8及TNF-α水平、并发症总发生率及复发率均低于对照组(P<0.05)。治疗后,两组躯体功能、心理功能、社会功能及物质生活评分均升高,且研究组高于对照组(P<0.05)。结论单纯修补术和胃大部分切除术治疗急性胃穿孔均有一定的临床效果,但前者对血清炎症子因刺激较少,并发症发生率及复发率较低,对提高患者术后生活质量及临床疗效具有积极作用,值得临床推广。
Objective To compare the clinical effects of simple repair and subtotal gastrectomy on acute gastric perforation. Methods Sixty-six patients with acute gastric perforation admitted in our hospital from May 2017 to April 2018 were selected as the research objects and randomly divided into control group and research group, with 33 cases in each group. The control group was treated with subtotal gastrectomy, while the study group was treated with simple repair. The therapeutic effects of the two groups were compared. Results The total effective rate of treatment in the study group was higher than that of the control group(P<0.05). The amount of bleeding during operation in the study group was less than that in the control group, the operation time, the first exhaust time, the time of getting out of bed after operation and hospitalization time were shorter than those in the control group, the pain scores at 2 and 24 hours after operation were lower than those in the control group(P <0.05). The levels of C-reactive protein, IL-6, IL-8 and TNF-α, the total incidence of complications and the recurrence rate in the study group were lower than those in the control group(P<0.05).After treatment, the scores of physical function, psychological function, social function and material life in the two groups increased, and those in the study group were higher than the control group(P<0.05). Conclusion Simple repair and subtotal gastrectomy have certain clinical efficacy in treating acute gastric perforation, but the former has less stimulation to serum inflammatory factors, lower incidence of complications and recurrence rate, and has a positive effect on improving the quality of life and clinical efficacy of patients after operation, which is worthy of clinical promotion.
作者
高天丛
李保成
GAO Tian-cong;LI Bao-cheng(the Hospital of Chengcheng County, Weinan 715209;the First Hospital in Weinan, Weinan 714000, China)
出处
《临床医学研究与实践》
2019年第12期43-45,共3页
Clinical Research and Practice
