摘要
目的观察针刺联合抗抑郁药物治疗肿瘤患者抑郁状态的疗效。方法采用随机双盲对照设计,纳入肿瘤伴抑郁状态患者80例,随机分为治疗组(40例)和对照组(40例)。治疗组给予针刺联合抗抑郁药物治疗,针刺取四关穴(太冲、合谷)、百会、印堂;对照组单纯采用抗抑郁药物治疗。两组治疗疗程为3个月。比较两组治疗前后的汉密尔顿抑郁量表(HAMD)评分和健康问卷-9项(PHQ-9)评分的差异。结果两组患者治疗前HAMD评分[(25.20±4.29)分vs(24.13±4.20)分]和PHQ-9评分[(15.43±3.06)分vs(14.65±2.56)分]比较差异均无统计学意义(P>0.05)。与治疗前相比,治疗组治疗后HAMD评分[(12.33±3.56)分vs(25.20±4.29)]分和PHQ-9评分[(9.93±2.97)分vs(15.43±3.06)分]均降低,差异均有统计学意义(P<0.05)。与治疗前相比,对照组治疗后HAMD评分[(14.05±4.04)分vs(24.13±4.20)分]和PHQ-9评分[(11.73±3.08)分vs(14.65±2.56)分]均降低,差异均有统计学意义(P<0.05)。治疗组治疗后HAMD评分[(12.33±3.56)分vs(14.05±4.04)分]和PHQ-9评分[(9.93±2.97)分vs(11.73±3.08)分]均低于对照组,差异均有统计学意义(P<0.05)。结论针刺联合抗抑郁药物治疗肿瘤后抑郁的疗效较好,无明显不良反应。
Objective To investigate the therapeutic effect of acupuncture on depression in tumor patients. Method A randomized double-blind controlled trial was carried out. Eighty tumor patients with depression were randomized to a treatment group (40 cases) and a control group (40 cases). The treatment group received acupuncture at Siguan points [Taichong (LR3) and Hegu (LI4)] and points Baihui (GV20) and Yintang (Ex-HN3) plus the oral administration of antidepressants and the control group, the oral administration of antidepressants alone. The course of treatment was three months in both groups. The Hamilton Depression Rating Scale (HAMD) scores and the 9-item Patient Health Questionnaire (PHQ-9) scores were compared between the two groups before and after treatment. Result There were no statistically significant pre-treatment differences in the HAMD score [(25.20±4.29) vs (24.13±4.20)] and the PHQ-9 score [(15.43±3.06) vs (14.65±2.56)] between the two groups of patients (P>0.05). Both the HAMD score [(12.33±3.56) vs (25.20±4.29)] and the PHQ-9 score [(9.93±2.97) vs (15.43±3.06)] decreased in the treatment group after treatment compared with before with statistically significant differences (both P<0.05). Both the HAMD score [(14.05±4.04) vs (24.13±4.20)] and the PHQ-9 score [(11.73±3.08) vs (14.65±2.56)] decreased in the treatment group after treatment compared with before with statistically significant differences (both P<0.05). After treatment, both the HAMD score [(12.33±3.56) vs (14.05±4.04)] and the PHQ-9 score [(9.93±2.97) vs (11.73±3.08)] were lower in the treatment group than in the control group with statistically significant differences (both P< 0.05). Conclusion Acupuncture has a better therapeutic effect on depression following tumor without obvious adverse reactions.
作者
刘艳屏
王玉
付林
肖倩
刘翔
LIU Yan-ping;WANG Yu;FU Lin;XIAO Qian;LIU Xiang(Wuhan Fifth Hospital,Wuhan 430050,China;Hubei Tumor Hospital,Wuhan 430070,China)
出处
《上海针灸杂志》
2019年第4期417-420,共4页
Shanghai Journal of Acupuncture and Moxibustion
关键词
针刺疗法
肿瘤
抑郁
汉密尔顿抑郁量表
健康问卷-9项
Acupuncture therapy
Tumor
Depression
Hamilton Depression Rating Scale
9-item Patient Health Questionnaire
