摘要
Objective To investigate the changes of brain gray matter volume in patients with occupational noise-induced hearing loss by voxel based morphometry(VBM).Methods 16 age-and education-matched healthy controls and 42 patients with occupational noise induced hearing loss,including 27 in mild group and 15 in severe group,received MRI 3D-FSPGR sequence T1WI sagittal scan,and then underwent VBM of brain gray matter volume data analysis.Results The brain gray matter volume of the left occipitotemporal lateral gyrus,the anterior cingulate gyrus,the bilateral angular gyrus,the precuneus and the near midline area of cerebellum differed between the experimental group and the control group(P<0.01).Conclusion The volume of gray matter in specific brain areas of patients with occupational noise-induced hearing loss changed,and the effect of noise on brain structure was revealed from the perspective of imaging.
