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子宫颈感染孢子丝菌1例

A case of sporotrichosis in the uterine cervix
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摘要 目的探讨双相真菌申克孢子丝菌(复合体)子宫颈感染的临床特点,为进一步提高实验室及临床诊断水平提供资料。方法分析1例申克孢子丝菌(复合体)子宫颈感染临床表现与实验室诊断过程,检索近年来国内外主要文献进行复习。结果患者阴道分泌物镜检见成团的革兰染色阳性、圆形、卵圆形孢子,较球菌大,较酵母样真菌孢子小。37℃血平皿培养,形成边缘不齐、表面有褶皱、干燥、有韧性不易挑取的白色菌落;革兰氏染色镜下见染色阳性酵母样芽生孢子。25℃SDA培养,形成中心有白色褶皱,周围绒毛样的丝状真菌菌落形态,直接涂片镜检见大量有隔菌丝、孢子。上述特征符合申克孢子丝菌。国内外文献检索,申克孢子丝菌感染多为皮肤局限性、肺炎、骨关节等病例,偶有累及局部淋巴结的病例,仅少数艾滋病等免疫力极度低下患者为全身播散性感染。结论申克孢子丝菌所致子宫颈感染罕见,掌握其在人体内与不同条件下培养菌落的特征有助于及时诊断。 Objective To investigate the clinical characteristics of sporotrichosis in the uterine cervix caused by Sporothrix schenckii ). Methods A case of Sporothrix schenckii in the uterine cervixhad been analyzed. Review of major related literatures at domestic and foreign in recent years was also performed. Results Microscope examination of vaginal secretions showed lumpy, Gram-positive, round-shaped and oval-spores, which were larger than normal Gram-positive coccus and smaller than yeast-like fungal spores. Blood plate culture at 37℃ showed white colony with marginal edges, dry and wrinkled surface. It was not easy to pick up sample from the tough surface. The Gram stain of this white colony showed Gram-positive yeast-like spores. The, filamentous fungus-like colonies with white folds in centerhas been formed at 25℃ in the SDA culture. These characteristics were consistent with clinical laboratory diagnostic features of Sporothrix schenckii infection. Conclusion The cervix infection caused by Sporothrix schenckii was rare, and the characteristics of culturing colonies under different conditions would be helpful to timely diagnosis in the laboratory.
作者 张一男 刘晓娜 杨晶 刘玥姣 石铭 薛文成 ZHANG Yin-an;LIU Xiao-na;YANG Jing;LIU Yue-jiao;SHI Ming;XUE Wen-cheng(Department of Laboratory Medicine,Dalian Jiuzhou Century Hospital. Dalian 116400,China;Gynecology Department,Dalian Jiuzhou Century Hospital. Dalian 116400,China)
出处 《中国真菌学杂志》 CSCD 2019年第1期47-49,共3页 Chinese Journal of Mycology
关键词 双相真菌 申克孢子丝菌 子宫颈 感染 dimorphism fungi sporotrichosis uterine cervix infection
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