摘要
肠道菌群通过宿主与饮食交互作用在机体的脂质代谢过程中扮演着十分重要的角色。食物中广泛存在的膳食纤维及肠道菌群代谢的产物可选择性地改变肠道菌群组成,进而提高肠道短链脂肪酸水平、降低炎性因子表达水平、影响饥饿禁食诱导因子表达,从而改善机体的脂质代谢水平。膳食纤维这种通过改善肠道菌群组成来调节机体脂质代谢的生物活性作用,为预防和治疗脂质代谢紊乱等相关疾病提供了新的研究思路。本文在查阅文献的基础上,对膳食纤维经肠道微生态途径调节脂质代谢的活性作用及其机制进行了综述。
The intestinal flora plays a very important role in lipid metabolism through the interaction between host and diet.Dietary fibers from a wide variety of foods and their intestinal metabolites can improve lipid metabolism by selectively changing the gut microbiota composition,enhancing the level of short-chain fatty acids and decreasing the expression of proinflammatory cytokines and fasting-induced adipose factor(FIAF).Understanding the regulatory effect of dietary fibers on lipid metabolism by improving the gut microbiota composition provides new ideas for preventing and treating lipid metabolism disorder and related diseases.This article presents a review of the literature on the regulatory effect and mechanism of dietary fibers on lipid metabolism through the gut microbiota.
作者
王晨
钟赛意
邹宇晓
WANG Chen;ZHONG Saiyi;ZOU Yuxiao(College of Food Science and Technology,Guangdong Ocean University,Zhanjiang 524000,China;Key Laboratory of Functional Foods,Ministry of Agriculture,Guangdong Key Laboratory of Agricultural Products Processing,Sericultural and Agri-food Research Institute,Guangdong Academy of Agricultural Sciences,Guangzhou 510610,China)
出处
《食品科学》
EI
CAS
CSCD
北大核心
2019年第3期338-347,共10页
Food Science
基金
广东省科技计划项目(2017A050501022
2015B020234006)
广州市科技计划项目(2014J4500036)
广东省现代农业产业技术体系创新团队项目(2016LM1087
2016LM2151)
关键词
膳食纤维
肠道菌群
脂质代谢调节
作用机制
dietary fiber
gut microbiota
lipid metabolism regulation
mechanism
