摘要
胆囊息肉样病变(PLG)临床常见,以非肿瘤性息肉为主,少部分为肿瘤性息肉。总结了PLG的流行病学及相关危险因素,提示PLG的发病是由性别、HBV感染、代谢综合征、内脏肥胖、低密度脂蛋白低水平、胆囊壁增厚、糖尿病等多种因素共同作用所致。随着PLG的发病率日趋升高,认为今后的研究重点应着眼于运用流行病学研究结果,对高危人群定期进行健康筛查,并对确诊患者进行规范化随访观察,发现并及早干预具有癌变可能的PLG。
Polypoid lesions of the gallbladder(PLG)is a common gallbladder disease in clinical practice.Most patients have non-adenomatous polyps,while adenomatous polyps are observed in a small number of patients.This article summarizes the epidemiology of PLG and related risk factors and points out that PLG is caused by the combined effect of various factors including sex,hepatitis B virus infection,metabolic syndrome,visceral obesity,a low level of low-density lipoprotein,gallbladder wall thickening,and diabetes.With the gradual increase in the incidence rate of PLG,epidemiological data should be used for health screening among the high-risk population,and standardized follow-up should be performed for patients with a confirmed diagnosis.PLG which may progress to cancer should be identified and intervention should be given as early as possible.
作者
陈善鹏
王智翔
张小弟
沈乃营
魏志力
CHEN Shanpeng;WANG Zhixiang;ZHANG Xiaodi(Department of General Surgery,215 Hospital of Nuclear Industry Affiliated to Xi′an Medical University,Xianyang,Shaanxi 712000,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2019年第2期441-443,共3页
Journal of Clinical Hepatology
关键词
胆囊疾病
息肉
流行病学
危险因素
综述
gallbladder diseases
polyps
epidemiology
risk factors
review