摘要
目的:研究甲状腺癌根治术后患者口服钙剂及维生素D预防低钙血症的效果。方法:选择本院于2015年1月-2016年1月30例行甲状腺癌根治术患者,纳入对照组,术后行常规用药治疗;于2016年2月-2017年1月随机抽取30例行甲状腺癌根治术患者,纳入观察组,术后在常规治疗基础上增加口服钙剂及维生素D。观察并比较两组患者低钙血症发生率与术前及术后1 d、7 d、出院3个月血清钙、甲状旁腺激素指标值。结果:观察组术后低钙血症发生率低于对照组(x^2=9.886,P=0.002)。血清钙<2 mmol/L患者,观察组有3例(10.00%),对照组有11例(36.67%),两组比较差异有统计学意义(x^2=19.880,P=0.000)。两组术前血清钙、甲状旁腺激素指标值比较,差异均无统计学意义(P>0.05);术后1、7 d以及出院3个月,观察组患者甲状旁腺激素水平均优于对照组(t=4.676、4.402、4.899,P=0.000、0.000、0.000);术后7 d、出院3个月,观察组血清钙水平均优于对照组(P<0.05)。结论:对甲状腺癌行根治术后患者早期补充维生素D和钙剂,可有效预防术后低钙血症发生。
Objective:To study the effect of oral calcium and Vitamin D on prevention of hypocalcemia in patients with thyroid carcinoma after radical operation.Method:30 patients undergoing radical thyroidectomy in our hospital from January 2015 to January 2016 were included in the control group and treated with routine medication after operation;from February 2016 to January 2017,30 patients undergoing radical thyroidectomy were randomly selected and included in the observation group,after operation,oral calcium and Vitamin D were added on the basis of routine treatment.The incidence of hypocalcemia and preoperative and postoperative 1 d,7 d,3 months after the serum calcium,parathyroid hormone index value of the two groups were observed and compared.Result:The incidence of hypocalcemia in the observation group was significantly higher than that in the control group(Χ2=9.886,P=0.002).In the patients with serum calcium<2 mmol/L,there were 3 cases(10.00%)in the observation group and 11 cases(36.67%)in the control group,the difference was statistically significant between the two groups(Χ2=19.880,P=0.000).There were no significant differences in serum calcium and parathyroid hormone index before operation(P>0.05).After operation 1 d,7 d,and 3 months discharged from hospital,the levels of parathyroid control group(t=4.676,4.402,4.899;P=0.000,0.000,0.000).7 d after operation and 3 months discharged from hospital,the average serum calcium water in the observation group were better than those of the control group(P<0.05).Conclusion:The early addition of vitamin D and calcium to patients with thyroid carcinoma after radical operation can effectively prevent the occurrence of postoperative hypocalcemia.hormone in the observation group were better than those of the
作者
黄飞
邱昌洪
HUANG Fei;QIU Changhong(The First People’s Hospital of Zhaoqing,Zhaoqing 526000,China)
出处
《中国医学创新》
CAS
2018年第3期39-42,共4页
Medical Innovation of China
基金
肇庆市科技创新计划立项项目(2016040307)
关键词
低钙血症
甲状腺癌
血清钙
甲状旁腺激素
Hypocalcemia
Thyroid cancer
Serum calcium
Parathyroid hormone
