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三联体常染色体STR三带型基因座父权指数计算 被引量:10

Paternity Index Calculated from the Parents-offspring-triadic Autosomal STR Shown in Three-banded Patterns
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摘要 目的探讨三联体亲子鉴定中常染色体STR三带型基因座父权指数的计算方法。方法通过9691例三联体亲子鉴定中发现的30例三带型,对其父-母-子表型作分析研究而将相关三带型分为五类,根据孟德尔遗传规律和常规三联体父权指数的计算原理,推算各类型的父权指数。结果循例推断出五种类型三联体常染色体STR三带型基因座父权指数的计算公式。结论对于三联体亲子鉴定中的三带型基因座,其父权指数可按推导的公式进行计算。 Objective To discuss how to calculate the paternity index of autosomal three-banded-pattern STRs appeared in parents-offspring-triadic paternity testing.Methods Based on the30pieces showing three-banded-pattern STRs detected from9691cases of parents-offspring-triadic paternity testing,the three-banded patterns were divided into five types by the phenotypes of each father-mother-child triad.According to Mendel’s laws of inheritance and the calculation principle of the conventional parents-offspring-triadic paternity index,the paternity indexes were calculated on the five-type threebanded patterns.Results For the five types of three-banded-patterns,the formulas were established about the paternity index of parents-offspring-triad autosomal STRs from specific examples.Conclusion For the three-banded patterns shown from autosomal STR parents-offspring-triad paternity testing,the paternity index can be calculated by the correlative formula here.
作者 刘芳 任贺 陈冲 石妍 刘莹 LIU Fang;REN He;CHEN Chong;SHI Yan;LIU Ying(Criminal Investigation Division, Changping Branch of Beijing Public Security Bureau, Beijing 102200, China;Beijing Police College, Beijing 102202, China;Beijing TongdaShoucheng Institute of Forensic Science, Beijing 100192, China;Forensic Medical Identification Centre of Beijing Public Security Bureau, Beijing 100192, China;Judicial Identification Institute of Gansu Dian Sharing Medical Laboratories, Lanzhou 730046, China)
出处 《刑事技术》 2017年第6期471-475,共5页 Forensic Science and Technology
关键词 法医遗传学 三等位基因 三带型 三联体亲子鉴定 父权指数 forensic genetics tri-alleles three-banded patterns parents-offspring-triadic paternity testing paternity index
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