摘要
目的:探讨孕中期进行唐氏综合征筛查在产前诊断中的价值。方法:对1 620例孕妇测定孕中期血清标志物甲胎蛋白、游离雌三醇及绒毛膜促性腺激素含量,再采用唐氏综合征筛查相关的风险评估软件计算风险值,得出阳性率。结果:高风险率占筛查总数5.0%,羊水穿刺诊断异常检出率100%。结论:孕中期通过唐氏综合征筛查进行产前筛查风险分析,可有效提高产前诊断的异常检出率,作为预测异常胎儿的有效指标。结合羊水穿刺等产前诊断技术和方法,对预防、减少先天缺陷儿有重要临床应用价值。
Objective:To investigate the value of prenatal screening in prenatal screening for Down's syndrome.Methods:1620cases of pregnant women were measured serum markers in the second trimester of AFP,three female alcohol free and hCG content,and thetn the risk value of Down's syndrome was calculated by the risk assessment software related to Down's screening.Results:The high risk rate accounted for5%of the total number of screening,and the abnormal rate of amniocentesis diagnosis was100%.Conclusion:The risk analysis of prenatal screening by Down's screening during the second trimester can effectively improve theabnormal detection rate of prenatal diagnosis,and it is an effective index for predicting abnormal fetus.Combined withamniocentesis and other prenatal diagnosis techniques and methods,it has important clinical value in preventing and reducing thebirth of congenital defects.
作者
李慧君
李德君
豆媛媛
Li Huijun;Li Dejun;Dou Yuanyuan(Maternal and Child Health Care Hospital of Urumqi City 830011)
出处
《中国社区医师》
2017年第29期102-103,共2页
Chinese Community Doctors
关键词
唐氏筛查
产前诊断
孕中期
Down's screen
Prenatal diagnosis
Second trimester
