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高敏C反应蛋白对急性ST段抬高型心肌梗死患者近期预后的预测价值分析 被引量:10

Prognostic value of hypersensitive C reactive protein in patients with acute ST segment elevation myocardial infarction
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摘要 目的:探讨分析高敏C反应蛋白(high sensitivity C-reactive protein,hs CRP)对急性ST段抬高型心肌梗死患者近期预后的预测价值。方法:选取本院2012年11月至2014年7月期间住院治疗的108例ST段抬高型心肌梗死患者作为研究分析对象,回顾分析患者的临床资料,所选患者入院均接受hs CRP检测,按照检测结果将所选患者分为A、B组,比较两组患者临床状况。结果:比较A、B两组患者近期预后状况,从心力衰竭、心绞痛、恶性心律失常等方面比较,A、B两组存在明显差异,且数据具有统计学意义(P<0.05)。从总病死率方面进行比较,A组(4.76%)与B组(1.51%)差异不具统计学意义(P=0.187)。分析与心血管疾病的相关因素,并将所分析的因素列入多元回归方程中,结果显示,心血管疾病独立预测因子和年龄、hs CRP、左心室射血分数、糖尿病等因素有关(P<0.05)。结论:hs CRP可预测急性ST段抬高型心肌梗死患者近期状况,特别是恶性心律失常、心绞痛、心力衰竭的发生。 Objective: To investigate and analyse the predictive value of high sensitivity C-reactive protein ( hs CRP) on theshort - term prognosis in patients with acute ST segment elevation myocardial infarction. Methods: 108 patients with ST segment elevationmyocardial infarction treated by our hospital from November 2012 to July 2014 were selected as the research object, and the clinicaldata of all patients were analyzed retrospectively. All patients were selected to receive hsCRP detection. The patients were divided intoA and B groups according to the test results, and the clinical status of the two groups were compared. Results:Compared with A ,B twogroups of patients in the near future,from psychological failure, angina, malignant arrhythmia, B , A two groups were significantly different,and the data were statistically significant (P <0. 05). From the total mortality rate, there was no significant difference betweengroup A and B group (4. 76% vs 1.51% ,P = 0. 187). Related factors of cardiovascular disease were analyzed in the multiple regressionequation. The results showed that age, hsCRP, left ventricular ejection fraction, diabetes were independently predicted factors of cardiovasculardisease( P < 0. 05). Conclusion: The situation of recent prognosis of patients with acute ST segment elevation myocardialinfarction patients detected with hsCRP were taken to determ ine, hsCRP can predict the recent situation of the disease, especially the occurrenceof malignant arrhythmia, angina and heart failure.
作者 杜柯君 DU Ke-jun
出处 《川北医学院学报》 CAS 2016年第3期328-330,共3页 Journal of North Sichuan Medical College
基金 四川省教育厅自然科学项目(2010ZA169)
关键词 心肌梗死 急性ST段抬高型 高敏C反应蛋白 Miocardial infarction Acute ST segment elevation Hypersensitive C reactive protein
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