摘要
5～15岁的HBV易感儿童,按0、1、6月程序接种10μg×3乙型肝炎血源疫苗(北京生研所批号8615-1A、8722-2)。接种后1～2年他们的抗-HBs阳转率为～92％,无一例HBsAg阳转;未接种疫苗的对照组儿童,抗-HBs阳转率仅2.08％～2.60％,HBsAg阳转率分别为3.23％和2.08％。流行病学保护效果良好。易感少年儿童接种乙型肝炎血源疫苗将加快控制乙型肝炎的进程。
The anti-HBs seroconversion rate was about -92% in vaccinated group tested for two succesive years after completion of the vaccination schedule and no HBsAg was found among the vaccinees. HBsAg in the non-vaccinated control group was 2.08% and 3.23% respectively in first and second year observation period.The results indicate that the long/ml dosage vaccine schedule is good enough both in antigenecity and protection for children. It is desirable that immnnization should be extended to HBV susceptible children.
出处
《病毒学报》
CAS
CSCD
北大核心
1991年第A12期67-68,共2页
Chinese Journal of Virology
关键词
乙肝疫苗
免疫效果
血源
Plasma-derived hepatitis B vaccine
