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收住新生儿重症监护病房的产后巨细胞病毒感染新生儿的胃肠道表现

Gastrointestinal manifestations of postnatal cytomegalo virus infection in infants admitted to a neonatal intensive care unit over a five year period
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摘要 一所新生儿重症监护病房在5年内收治的患儿中,有16例被确诊为出生后巨细胞病毒(CMV)感染。其中,11例患儿在分娩过程中出现胃肠道表现。患儿的胃肠道表现多样,轻重不等。 Sixteen cases of postnatal cytomegalovirus (CMV) infection were identified in a neonatal intensive care unit population over a five year period. Eleven of these infants had gastrointestinal signs at the time of presentation. These ranged from minor and transient (abdominal distension and enteral feed intolerance) to severe and life threatening (protein losing enteropathy, diarrhoea, and hypernatraemic dehydration) . An initial diagnosis of necrotising enterocolitis was common, but no infant showed intestinal or hepatic portal pneumatosis. The gestational age of the infants was 24 - 38 weeks. All had received fresh maternal breast milk. It is suggested that CMV enteritis is added to the spectrum of clinical manifestations of postnatal CMV infection. Signs suggestive of necrotising enterocolitis with atypical features should prompt investigations for CMV infection.
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