摘要
目的 了解葡萄球菌致病性及耐药性 ,为合理使用抗生素、有效控制医院感染提供参考。方法 对医院感染患者标本中分离的 3 0 5株葡萄球菌作菌种鉴定。分别用琼脂稀释法、K -B法及SceptorMIC/ID法进行抗生素敏感性测定。结果 在 3 0 5株葡萄球菌中 ,凝固酶阳性者占 5 0 .4% ,凝固酶阴性者占 49.6%。院内感染葡萄球菌的耐药性均较强 ,特别是耐甲氧西林葡萄球菌 (MRS)。结论 医院感染的葡萄球菌常表现为多重耐药 。
Objective To investigate the pathogenicity and drug resistance of staphylococcus for rational application of antibiotics. and effective control of nosocomial infection.Methods 305 strians of staphylococci from the samples of the patients of nosocomial infection were identified. The antibiotic sensitivity was determined with Agar-dilution,Kirby-Bauer diffusion and Sceptor MIC/ID methods.Results The coagulase-positive staphylococcus was 50.4% and the coagulase-negative staphylococcus was 49.6% in 305 strians. The resistant rate of staphylococcus in hospital infection was high,especially of methicillin-resistant staphylococcus (MRS).Conclusion Staphylococcus in nosocomial infection showed multi-resistance to antibiotics. It is very important to use antibiotics rationally for controlling the infections caused by staphylococcus in hospitals.
出处
《同济大学学报（医学版）》
CAS
2002年第4期292-293,共2页
Journal of Tongji University(Medical Science)
关键词
葡萄球菌
分离
鉴定
耐药性
监测
医院内感染
staphylococcus
methicillin-resistant staphylococcus
resistance
nosocomial infection
