摘要
扩散加权成像(DWI)理论认为组织中的水分子扩散是一种单纯扩散,并通过单指数模型定量计算组织中的水分子受限程度。而体素内不相干运动(IVIM)理论认为,组织中的水分子扩散是一种非高斯扩散,且这些水分子扩散信息包含组织中的毛细血管灌注信息,临床上常用双指数模型定量计算水分子扩散的受限程度与毛细血管灌注信息。其中,DWI具有扫描时间短、图像质量高等优势,而IVIM在实性病灶的良恶性鉴别、恶性病灶病理分级、治疗后评估等方面取得新突破。对于DWI与IVIM的更多临床应用价值需要以后进一步研究。
Diffusion weighted imaging（DWI） theory holds that the diffusion of water molecules in tissues is a simple diffusion, which calculates the degree of water molecules confinement in tissues by a single exponential model. The theory of introvoxel incoherent motion（ IVIM ） theory holds that the diffusion of water molecules in tissue is not only a Gauss diffusion, and these water molecular diffusion information contains eapillary perfusion information in tissue. In clinical practice, a hi-exponential model is frequently used to quantitatively calculate the degree of diffusion of water molecules and eapillary perfusion information. DWI has obvious advantages in short scanning time and high image quality,while IVIM has made new breakthroughs in the differentiation of benign and malignant lesions, pathological grading of malignant lesions, and evaluation after treatment. In the future, the clinical applicative value of DWI and IVIM needs further study.
作者
陶奉明
刘爱连
刘静红
陈丽华
TAO Fengming;LIU Ailian;LIU Jinghong;CHEN Lihua(Department of Radiology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China)
出处
《医学综述》
2018年第19期3893-3896,3903,共5页
Medical Recapitulate
