摘要
目的观察有性生活老年男性血清游离睾酮(FT)水平与总睾酮(TT)的相关性。方法将重庆市第十三人民医院、重庆市人民医院、重庆医科大学附属永川医院及重庆市第四人民医院4个医院随机收集的1 709例有性生活的老年男性作为研究对象。按有无高危性行为将其分为有高危性行为者(305例)和无高危性行为者(1 404例);按不同年龄将研究对象分为60~<65岁组(998例)、65~<70岁组(435例)、70~<75岁组(162例)、75~<80岁组(82例)和≥80岁组(32例)5个年龄组。分别采用放射免疫法和化学发光分析法测定全部研究对象的血清FT和TT值,分析总体、有无高危性行为和不同年龄段3种情况下血清FT与TT的相关性。结果在1 709例研究对象中,血清FT平均值为(8.18±2.23)pg/mL,血清TT平均值为(11.52±3.28)nmol/L,二者具有极强的正相关性(rs=0.836,P<0.01)。在有高危性行为者中,血清FT平均值为(10.72±2.19)pg/mL,血清TT平均值为(16.23±3.44)nmol/L,二者的秩相关系数rs为0.694(P<0.01);在无高危性行为者中,血清FT平均值为(7.63±1.82)pg/mL,血清TT平均值为(10.49±2.16)nmol/L,二者的秩相关系数rs为0.803(P<0.01)。不同年龄组的血清FT与TT之间也同样有着极强的正相关性(rs分别为0.800、0.858、0.780、0.919、0.914,P<0.01)。结论有性生活老年男性的血清FT水平与TT具有极强的正相关性,可通过检测的血清TT值来反映FT水平。
Objective To observe the correlation between serum free testosterone（FT）level and total testosterone（TT）level in elderly males with sexual life.Methods A total of 1 709 elderly males with sexual life randomly collected from 4 hospitals of Chongqing Municipal Thirteenth People′s Hospital,Chongqing Municipal People′s Hospital,Affiliated Yongchuan Hospital of Chongqing Medical University and Chongqing Municipal Fourth People′s Hospital served as the research subjects and divided into the high risk sexual behavior males（305 cases）and non-high risk sexual behavior males（1 404 cases）according to whether the subjects having high-risk sexual behavior;the research subjects were classified as the five age groups of 60-65 years old（998 cases）,65-70 years old（435 cases）,70-75 years old（162 cases）,75-80 years old（82 cases）and≥80 years old（32 cases）.Serum FT and TT values of all research subjects were determined by using the radioimmunoassay and chemiluminescence analytical methods.Under the cases of totality,whether having high risk sexual behavior and different age groups,the correlation between serum FT and TT was analyzed.Results Among 1 709 research subjects,the serum FT average value was（8.18±2.23）pg/mL,and the serum TT average value was（11.52±3.28）nmol/L,and they had an extremely strong positive correlation（rs=0.836,P〈0.01）.Among the subjects with high-risk sexual behavior,the serum FT average value was（10.72±2.19）pg/mL,the serum TT average value was（16.23±3.44）nmol/L,their rank correlation coefficient was 0.694（P〈0.01）;among the subjects without high-risk sexual behavior,the serum FT average value was（7.63±1.82）pg/mL,and the serum TT average was（10.49±2.16）nmol/L,and their rank correlation coefficient was 0.803（P〈0.01）.There was also an extremely strong positive correlation between serum FT and TT in different age groups（rswere 0.800,0.858,0.780,0.919 and 0.914 respectively,P〈0.01）.Conclusion Serum FT level has an extremely strong positive correlation with serum TT level in elderly males with sexual life,and detecting serum TT levels can reflect serum FT level.
作者
赵凤兰
龚宇
易红
彭斌
肖贵元
胡莹
钟晓妮
贾瑜
周维康
雷山川
ZHAO Fenglan;GONG Yu;YI Hong;PENG Bin;XIAO Guiyuan;HU Ying;ZHONG Xiaoni;JIA Yu;ZHOU Weikang;LEI Shanchuan(Department of Dermatology,Chongqing Municipal Thirteenth People′s Hospital/ChongqingMunicipal Geriatric Hospital,Chongqing 400053,China;Teaching and Researching Section ofStatistics,College of Public Health and Management,Chongqing Medical University,Chongqing 400016,China;Department of Dermatology,Chongqing MunicipalFourth People′s Hospital,Chongqing 400014,China;Department of Dermatology,ChongqingMunicipal People′s Hospital,Chongqing 400014,China;Department of Dermatology,AffiliatedYongchuan Hospital,Chongqing Medical University,Chongqing 402160,China)
出处
《检验医学与临床》
CAS
2018年第20期3005-3007,3010,共4页
Laboratory Medicine and Clinic
基金
重庆市卫生和计划生育委员会医学科研重点项目(2015ZDXM025)
关键词
游离睾酮
总睾酮
老年
男性
free testosterone
total testosterone
the elderly
men
