摘要
目的探讨综合干预在非酒精性脂肪肝(NAFLD)患者的应用效果。方法选取2016年1月～2017年1月我院收治的56例NAFLD患者作为研究对象,随机分为干预组和对照组,每组各28例。干预组给予综合干预,对照组给予常规干预,观察患者肝功能、尿酸、血脂、血糖、肝脏硬度变化情况。结果干预后,两组患者的血清碱性磷酸酶(ALP)、天门冬氨酸转氨酶(AST)、血清丙氨酸转氨酶(ALT)水平均有所下降,且干预组低于对照组,差异有统计学意义(P<0.05);干预后,干预组的血清总胆固醇(TC)、三酰甘油(TG)、空腹血糖(FBG)、空腹胰岛素(FINS)以及Fibro Scan脂肪含量CAP值均低于对照组,差异有统计学意义(P<0.05)。结论对NAFLD患者行综合干预,可帮助患者建立健康的生活方式,控制血糖,改善患者肝功能,值得临床推广。
Objective To explore the application effect of comprehensive intervention in patients with non-alcoholic fatty liver disease （NAFLD）. Methods A total of 56 cases of patients with NAFLD treated in our hospital from January 2016 to January 2017 were selected as the subjects, and randomly divided into intervention group and control group, with 28 cases in each group. The intervention group were given the comprehensive intervention, while the control group were given routine intervention. The changes of liver function, uric acid, blood lipid, blood sugar and liver hardness of patients were observed. Results After the intervention, the levels of ALP, AST and ALT of two groups were decreased, and the index in the intervention group were lower than those in the control group, the differences were statistically sig- nificant （P〈0.05）. After the intervention, the TC, TG, FBG, FINS and CAP value of FibroScan fat content in the inter- vention group was significantly lower than those in the control group, the differences were statistically significant （P〈 0.05）. Conclusion The comprehensive intervention for patients with NAFLD can help patients establish healthy lifestyles, control blood sugar and improve their liver function, which is worthy to be promoted in the clinical.
作者
刘艳红
陈少文
周南南
LIU Yan-hong;CHEN Shao-wen;ZHOU Nan-nan(Department of Infectious Disease,Shekou People＇s Hospital of Nanshan District in Shenzhen City,Guangdong Province,Shenzhen 518067,China)
出处
《中国当代医药》
2018年第27期54-57,共4页
China Modern Medicine
关键词
运动行为干预
饮食干预
非酒精性脂肪肝
Exercise behavior intervention
Diet intervention
Non-alcoholic fatty liver disease
