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选择性脾部分栓塞术在治疗Ⅰ~Ⅱ级外伤性脾破裂中的应用价值分析 被引量:16

Value of selective splenic embolization in the treatment of Ⅰ~Ⅱ grade traumatic rupture of the spleen
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摘要 目的:探讨选择性脾部分栓塞术在治疗I-II级外伤性脾破裂中的应用价值。方法:选取江油市九O三医院收治的100例Ⅰ~Ⅱ级外伤性脾破裂患者作为研究对象,根据手术方法分为A组61例(脾切除术组)、B组39例(介入组),对比两种方法的手术时间、输血量、住院时间、手术成功率及手术前后患者免疫状况的变化。结果:A组患者的手术时间、输血量、住院时间显著高于B组(P<0.05);A组的手术成功率(90.16%)与B组的(94.87%)比较差异无统计学意义(P>0.05);术后14 d及28 d,A组的CD3+、CD4+、CD4+/CD8+水平显著低于B组(P<0.05),A组的CD8+显著高于B组(P<0.05);术后14 d及28d,A组的Ig A、Ig G、Ig M水平显著低于B组(P<0.05);A组患者的手术并发症率与B组比较差异无统计学意义(P>0.05)。结论:选择性脾部分栓塞术对Ⅰ~Ⅱ级外伤性脾破裂患者的手术效果与脾切除术效果相当,但创伤较小、术后患者免疫功能恢复较快。 ObJective: To evaluate the value of selective splenic embolization in the treatment of Ⅰ-Ⅱ traumatic rupture of the spleen. Methods: A total of 100 patients with Ⅰ-Ⅱtraumatic rupture of the spleen ruptured at Nine 03 Hospital of Jiangyou were enrolled in this study. They were divided into two groups according to the surgical methods: 61 cases in group A (splenectomy group), 39 cases in group B(intervention group) .Compare the two methods of operation time, blood transfu- sion, hospital stay, the success rate of surgery and changes in patients with immune status before and after surgery. Results: The operation time, blood transfusion and hospital stay in group A were significantly higher than those in group B (P〈0.05). The success rate of operation in group A was 90.16% and 94.87% in group B, respectively, with no significant difference between the two groups(P〉0.05); The levels of CD3+, CD4+ and CD4+/CD8+ in group A were significantly lower than those in group B on day 14 and day 28(P〈0.05), and were significantly higher in group A than those in group B(P〈0.05). The levels of IgA, IgG and IgM in group A were significantly lower than those in group B at 14 and 28 days after operation (P〈0.05). The operative complication rate in group A was 11.48%, which was not significantly different from that of group B (P〉0.05). Conclusion: Selective partial splenic embolization has similar efficacy to splenectomy in patients with grade Ⅰ-Ⅱ traumatic splenic rupture, but less trauma and faster recovery of immune function after surgery.
作者 柏宇 Bo Yu(Department of Second Surgery, Jiangyou 903 Hospital(Jiangyou 621700, China))
出处 《中国现代普通外科进展》 CAS 2018年第8期616-618,622,共4页 Chinese Journal of Current Advances in General Surgery
关键词 脾切除 部分脾动脉栓塞 外伤性脾破裂 Partial splenectomy Partial splenic embolization Splenic traumatic rupture
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