摘要
皮肤黑色素代谢是一个复杂精细的调控过程，由多个基因多种酶及蛋白相互协同调控。随着对影响皮肤黑色素代谢因素研究的深入，科学家发现干细胞因子受体c—kit与其配体干细胞因子结合后启动的信号通路在皮肤黑色素代谢中发挥了极为重要的作用。该文就c—kit受体在皮肤黑色素代谢过程中的的作用、分子机制和临床应用的最新研究进展进行了总结。
Skin melanin metabolism is a complex and fine regulation process, which is controlled by multiple genes, many enzymes and proteins. With the in-depth study of the factors affecting the skin melanin metabolism, scientists have found that the signaling pathway initiated by the combination of stem cell factor receptor c-kit and its ligand stem cell factor plays an important role in the metabolism of skin melanin. The paper summarizes the recent research progress on the role of c-kit receptor in the skin melanin metabolism, including the molecular mechanism and the clinical application.
作者
平宇
曹莫
Ping Yu;Cao Mo(Department of Plastic,Third Hospital of Hebei Medical University,Shijiazhuang 050051,China)
出处
《中华整形外科杂志》
CAS
CSCD
北大核心
2018年第8期671-675,647,共6页
Chinese Journal of Plastic Surgery
