摘要
目的探讨青鹏软膏联合中药口服治疗寻常性斑块状银屑病的疗效和安全性。方法2016年12月至2017年10月，将郑州市中医院60例寻常性斑块状银屑病患者分为两组。试验组30例给予青鹏软膏外用、中药口服治疗，对照组30例给予白凡士林外用、中药口服治疗，疗程4周。比较两组疗效，治疗前后进行银屑病皮损面积和严重程度指数（PASI）评分、瘙痒等级评分及安全性评价。结果试验组总有效率为93．33％，对照组为70．00％，差异有统计学意义（P〈0．05）。两组治疗后PASI评分、瘙痒等级评分均较治疗前显著降低（P〈0．05）。治疗后试验组在瘙痒等级评分方面显著优于对照组（P〈0．05）。两组均无明显不良反应。结论青鹏软膏联合中药口服治疗寻常性斑块状银屑病疗效确切，安全性好。
Objective To study the efficacy and safety of Qingpeng ointment combined with oral Chinese Medicine in the treatment of plaque psoriasis. Methods By a randomized controlled method, 60 patients with plaque psoriasis from December 2016 to October 2017 in Zhengzhou Hospital of Traditional Chinese Medicine were evenly divided into experimental group and control group. In the experimental group, patients were treated by Qingpeng ointment and oral Chinese Medicine, while in the control group, vaseline ointment and oral Chinese Medicine were provided. The period of treatment was 4 weeks. The PASI scores, itching index scores before and after treatment, clinical efficacy and security indices were compared between the two groups. Results The total effective rate was 93.33 % in the experimental group and 70.00% in the control group, which displayed a statistical difference （P〈0.05）. The PASI scores and itching index scores were significantly decreased in both groups after treatment （P〈0.05）. The value of itching index in the experimental group was lower than that in the control group after treatment, with a statistical difference （P〈0.05）. No adverse reactions occurred in the patients in the two groups. Conclusions Qingpeng ointment combined with oral Chinese medicine is effective and safe in the treatment of plaque psoriasis.
作者
李瑞婷
张琳琳
王晓丽
Li Ruiting;Zhang Linlin;Wang Xiaoli(Department of Dermatology,Zhengzhou Hospital of Traditional Chinese Medicine,Zhengzhou 450007,China)
出处
《中华医学美学美容杂志》
2018年第4期279-281,共3页
Chinese Journal of Medical Aesthetics and Cosmetology
关键词
银屑病
青鹏软膏
中药
Psoriasis
Qingpeng ointment
Chinese medicine
