摘要
采用体外实验和人体实验相结合方法,对5种中草药为原料制成的复方提取液进行美白、抗衰老、抗敏舒缓功效研究,并对其刺激性进行评价。结果表明,复方提取液的刺激性分级为无刺激性,具有较强的抑制酪氨酸酶活性、清除DPPH/羟基/超氧阴离子自由基及抑制透明质酸酶活性的能力;使用含复方提取液的乳液4周后,能显著减少皮肤黑色素含量和降低皮肤紫外斑、黄褐斑、皱纹、纹理分值;此外,含复方提取液的乳液能够降低乳酸刺痛程度。上述结果说明该复方中草药提取液使用安全性高,具有较好的美白、抗衰老、抗敏舒缓功效。
A combination of in vitro experiments and human efficacy evaluation were used to assess the whitening,anti-aging and anti-allergic soothing efficacy and the irritation of a compound extract which was obtained from 5 kinds of Chinese herbal medicines. The results show that the compound extract is classified as non-irritation substance. Besides,it has strong ability to inhibit tyrosinase activity,scavenge DPPH/hydroxyl/superoxide anion radicals and inhibit hyaluronidase activity. After 4 weeks of using the emulsion containing the compound extract,it can significantly reduce skin melanin content and decrease the scores of skin UV spots,chloasma,wrinkle and texture. In addition,this emulsion containing the compound extract can effectively relieve the tingling caused by lactic acid. The above results indicate that this compound extract is a safe and effective cosmetics raw material which has good whitening,anti-aging and anti-allergic soothing efficacy.
作者
刘芳
徐勇威
王珊珊
龚盛昭
LIU Fang;XU Yong-wei;WANG Shan-shan;GONG Sheng-zhao(Guangzhou Uniasia Cosmetic Technology Co.Ltd.,Guangzhou,Guangdong 510663,China;Guangdong Industry Technical College,Guangzhou,Guangdong 510300,China)
出处
《日用化学工业》
CAS
CSCD
北大核心
2018年第8期450-456,477,共8页
China Surfactant Detergent & Cosmetics
基金
广州市科技计划项目(201604016111)
关键词
化妆品
中草药
美白
抗衰老
抗过敏
刺激性
cosmetics
Chinese herbal medicine
whitening
anti - aging
anti - allergic
irritation
