摘要
目的探讨针药复合麻醉对老年患者术后炎性细胞因子和早期认知功能障碍的影响。方法选择2016年10月—2017年10月我院58例老年患者为研究对象,根据入院编号的奇偶数将其分为2组,其中对照组采用单纯全麻,观察组采用针药复合麻醉,对比2组效果。结果术前,2组MMSE评分比较无差异,P>0.05;术后,与对照组比较,观察组MMSE评分改善明显,P<0.05;与对照组比较,观察组术后24 h和48 h IL-1β、TNF-α以及IL-6水平均较低,P<0.05;同时,2组的麻醉苏醒时间、丙泊酚以及瑞芬太尼用量对比,P<0.05。结论给予老年患者针药复合麻醉有助于术后早期认识功能的恢复。
Objective To investigate the effects of acupuncture combined with drug anesthesia on postoperative inflammatory cytokines and early cognitive dysfunction in elderly patients. Methods In our hospital from October 2016 to October 2017, 58 elderly patients were selected as the research objects. According to the number of admission, they were divided into two groups. The control group adopted general anesthesia, and the observation group adopted acupuncture combined drug anesthesia. The effect of the two groups was compared. Results Before operation, there was no difference in MMSE scores between the two groups P 0.05. After operation,the MMSE score of the observation group was significantly improved comparing with the control group P 0.05. Comparing with the control group, 24 h and 48 hil-1, TNF-alpha and IL-6 were lower in the observation group P0.05. At the same time, the anesthetic wake time, propofol and remifentanil dosage were compared between the two groups P0.05. Conclusion The acupuncture combined with drug anesthesia is helpful to restore the function of early postoperative cognitive function.
作者
王洪南
WANG Hongnan(Department of Anesthesiology, the First Hospital of China Medical University, Liaoning Province, Shenyang 110001, Chin)
出处
《中国中医药现代远程教育》
2018年第16期99-100,共2页
Chinese Medicine Modern Distance Education of China
关键词
针药复合麻醉
炎性细胞
认知功能障碍
老年科
呆证
combined acupuncture and medicine anesthesia
inflammatotry cells
cognitive dysfunction
geriatrics
dementia
