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吸入糖皮质激素辅助治疗儿童肺炎支原体肺炎的临床疗效及安全性探讨 被引量:5

Investigation on Clinical Curative Effect and Safety of Inhaled Corticosteroid Adjuvant Therapy of Children with Mycoplasmal Pneumonia
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摘要 目的探究儿童肺炎支原体肺炎患儿在使用吸入糖皮质激素辅助治疗后的效果。方法研究对象为方便选取该院2015年6月—2016年6月治疗的96例儿童肺炎支原体肺炎患儿,按治疗方式不同随机分成观察组与对照组,48例观察组采用吸入常规治疗+糖皮质激素辅助治疗,另48例对照组采用常规治疗。探讨实施不同治疗对C反应蛋白(CRP)、临床症状、治疗效果及不良反应发生率的影响。结果观察组在CRP上显著比对照组低(t=25.186,P<0.05),且总有效率(97.92%)比对照组(89.58%)高(χ~2=5.935,P<0.05),不良反应发生率(2.08%)显著比对照组(10.42%)低(χ~2=5.935,P<0.05)。结论将吸入糖皮质激素辅助治疗应用于儿童肺炎支原体肺炎患儿时,不仅能提升治疗效果,改善临床症状,还能有效降低CRP,且不良反应发生率较低,此方法值得应用与推广。 Objective To study the clinical curative effect and safety of inhaled corticosteroid adjuvant therapy of children with mycoplasmal pneumonia. Methods 96 cases of children with mycoplasmal pneumonia admitted and treated in our hospital from June 2015 to June 2016 were convenient selected and randomly divided into two groups, with 48 cases in each,the observation group used the inhaled routine therapy and glucocorticoid adjunctive therapy, while the control group used the routine therapy, and the CRP, clinical symptoms, treatment effect and effect on the incidence rate of adverse reactions were studied. Results The CRP in the observation group was obviously lower than that in the control group(t=25.186, P〈0.05), and the total effective rate in the observation group was higher than that in the control group(97.92% vs 89.58%),(χ~2=5.935, P〈0.05), and the incidence rate of adverse reactions was obviously lower than that in the control group(2.08% vs10.42%),(χ~2=5.935, P〈0.05). Conclusion The application of inhaled corticosteroid adjuvant therapy of children with mycoplasmal pneumonia in the children with mycoplasmal pneumonia can improve the treatment effect, improve the clinical symptoms and effectively reduce the CRP with lower incidence rate of adverse reactions, and it is worth clinical promotion and application.
作者 林炎浩 LIN Yan-hao(Department of Pediatrics, Heyuan Heping Maternal and Infant Healthcare Hospital,Heyuan,Guangdong Province,517200 China)
出处 《中外医疗》 2018年第13期121-123,共3页 China & Foreign Medical Treatment
关键词 儿童肺炎 支原体肺炎 吸入糖皮质激素 辅助治疗 治疗效果 Children with pneumonia Mycoplasmal pneumonia Inhaled corticosteroid Adjuvant therapy Treatment effect
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