摘要
目的:观察补肾祛瘀通痹方治疗膝骨关节炎临床疗效及与股四头肌表面肌电信号相关性。方法:符合纳入标准膝骨关节炎患者80例,随机分为研究组及对照组,研究组给予补肾祛瘀通痹方口服,对照组给予盐酸氨基葡萄糖和双氯酚酸钠缓释片口服,观察4周。治疗结束后对患者进行临床疗效评价,评定治疗前后关节炎指数评分,比较两组患者治疗前后股四头肌积分肌电值与中位频率的变化情况。结果:研究组(92.50%,37/40)与对照组(77.50%,31/40)比较临床疗效显著,有显著性差异(P<0.05);研究组关节炎指数评分明显低于对照组,两者之间比较有显著性差异(P<0.05);研究组患侧股外侧肌、股内侧肌和股直肌的平均肌电值(AEMG)与对照组比较有显著性差异(P<0.05),中位频率(MF)明显高于对照组(P<0.05)。结论:补肾祛瘀通痹方治疗膝关节骨性关节炎临床疗效显著,能明显改善AEMG和MF,值得在临床上进一步推广。
Objective： To observe the effect of Bushen Quyu Tongbi Formula treating knee osteoarthritis（ KOA）and to study its correlation with AEMG signal of quadriceps femoris. Methods： 80 patients with KOA were randomly divided into the observation group and the control group; the observation group was treated with Bushen Quyu Tongbi Formula,and the control group was given Glucosamine Hydrochloride and Diclofenac Sodium.After four weeks,some indicators were evaluated,which include clinical efficacy,score of arthritis index,the changes of AEMG integral and median frequency of quadriceps femoris. Results： Compared to the control group（ 77. 50%,31/40）,the clinical efficacy of the observation group（ 92. 50%,37/40） was significant（ P〈0. 05）. Score of arthritis index of the observation group was significantly lower than that of the control group,there was significant difference between the two groups（ P〈0. 05）. There were significant differences,in terms of average AEMG of vastus lateralis,vastus medialis,and rectus femoris,between the observation group and the control group（ P〈0. 05）,and median frequency（ MF） of the observation group was significantly higher than that of the control group（ P〈0. 05）. Conclusion： Bushen Quyu Tongbi Formula has significant clinical efficacy in the treatment of KOA,it can obviously improve the levels of AEMG and MF,which deserves further promotion in clinical practice.
作者
黄霄汉
赵娟
张延杰
李继超
HUANG Xiaohan;ZHAO Juan;ZHANG Yanjie;LI Jichao(Luoyang Osteopathic Hospital,Luoyang 471002,China;Henan Vocational College of Tuina,Luoyang 471000,China)
出处
《中医药信息》
2018年第4期99-102,共4页
Information on Traditional Chinese Medicine
基金
2015年度河南省重点中医学科(专科)学术带头人培养项目专项课题(No.2015ZY03007)
