摘要
膜性肾病病理表现为肾小球基底膜上皮细胞下免疫复合物沉积伴弥漫性增生,临床以肾病综合征多见,也可表现为肾小球源性血尿,易发生血栓栓塞。本病可自发缓解,也可能进展为慢性肾衰竭。治疗上给予饮食调摄、降血压、降血糖、降血脂、抗凝血等基础治疗,对少量蛋白尿和(或)镜下血尿患者,可予血管紧张素转换酶抑制(ACEI)或血管紧张素Ⅱ受体拮抗剂(ARB)、中成药、中药饮片等治疗,对顽固性大量蛋白尿可予糖皮质激素和细胞毒药物。
The pathological manifestation of membranous nephropathy is the deposition of immune complex in the glomerular basement membrane epithelial cells with diffuse hyperplasia. The clinical manifestation of nephrotic syndrome is more common,it can also be expressed as glomerular hematuria,and thromboembolism is easy to occur. The disease can be relieved spontaneously,or it can progress to chronic renal failure. The basic treatment focuses on regulating diet,lowering blood pressure,lowering blood sugar,lowering blood lipids,anticoagulant,etc. For a small amount of proteinuria and/or microscopic hematuria,it can be treated with ACEI or ARB,Chinese patent medicine and Chinese prepared herbal slices,etc. For the intractable massive albuminuria,it can be treated with glucocorticoid and cytotoxic drugs.
作者
杜晓妹
王琳
DU Xiao-mei;WANG Lin(Minhang Branch of Yueyang Integrated Traditional Chinese and Western Medicine Hospital AMliated to Shanghai University of Traditional Chinese Medicine,Shanghai,China,200241;Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai,China,200032)
出处
《河南中医》
2018年第7期1122-1126,共5页
Henan Traditional Chinese Medicine
基金
国家自然科学基金项目(编号:81273730)
关键词
膜性肾病
中西医结合
肾病综合征
蛋白尿
membranous nephropathy
integrated traditional Chinese and western medicine
nephrotic syndrome
proteinuria
