摘要
目的观察对于慢性阻塞性肺疾病(COPD)合并呼吸衰竭行无创机械通气患者而言采用中西医结合治疗的疗效分析。方法选取该院2015年10月—2017年10月收治的COPD合并呼吸衰竭行无创机械通气患者138例,均分两组,每组69例。采取西医常规治疗为对照组,采用中西医结合治疗为联合组。将两组患者临床治疗效果与治疗前、后7 d分别检测炎症反应指标(IL-6、TNF-α、CRP)。结果疗程结束后联合组总有效率(97.10%)优于对照组(χ~2=34.794 9,P<0.05),且治疗后炎症指标水平IL-6(123.2±56.8)pg/m L、TNF-α(109.7±32.1)pg/m L、CRP(79.2±22.3)mg/L低于对照组,差异有统计学意义(t=4.528 1、4.219 9、10.243 4,P<0.001)。结论对于慢性阻塞性肺疾病合并呼吸衰竭机械通气患者而言,采用中西医结合治疗方式可有效降低患者血液中炎性反应指标,提高临床治疗效果理想。
Objective To observe the curative effect of combination of Chinese traditional and western medicine in treatment of patients with chronic obstructive pulmonary diseases and mechanical ventilation of respiratory failure.Methods 138 cases of patients with chronic obstructive pulmonary diseases and mechanical ventilation of respiratory failure admitted and treated in our hospital from October 2015 to October 2017 were selected and divided into two groups with 69 cases in each, the control group used the western medicine routine therapy, while the combined group used the combination of Chinese traditional and western medicine, and the clinical treatment effect, and test inflammatory reactive indicators such as IL-6,TNF-α,CRP before treatment and in 7 d after treatment were compared between the two groups. Results At the end of the treatment course, the total effective rate in the combined group was 97.10%,which was better than that in the control group（χ2=34.794 9,P〈0.05）, after treatment, the inflammatory index levels IL-6（123.2±56.8）pg/m L, TNF-α（109.7±32.1）pg/m L, CRP（79.2±22.3）mg/L were lower than those in the control group, and the differences were statistically significant（t=4.528 1,4.219 9,10.243 4,P〈0.001）. Conclusion The combination of Chinese traditional and western medicine in treatment of patients with chronic obstructive pulmonary diseases and mechanical ventilation of respiratory failure can effectively reduce the blood inflammatory reactive indicators and improve the clinical treatment effect.
作者
杨玮
YANG Wei(Guangdong First Rongjun Hospital,Guangzhou,Guangdong Province,510260 China)
出处
《系统医学》
2018年第4期25-26,29,共3页
Systems Medicine
关键词
中西医结合
慢性阻塞性肺疾病
呼吸衰竭
机械通气
疗效分析
Combination of Chinese traditional and western medicine
COPD
Respiration failure
Mechanical ventilation
Analysis of curative effect
