摘要
目的:对近5年来襄阳地区献血人群梅毒螺旋(TP)抗体的检测结果及感染趋势予以分析,为献血者招募策略及街头初筛方法的选择提供科学依据,最大限度保障血液安全。方法:应用2家不同的抗-TP酶联免疫试剂对献血人群展开筛查,对初筛阳性标本采用梅素螺旋体特异抗体颗粒凝集法(TP-PA)确认;利用χ2检验对结果进行统计分析。结果:360 711人份献血者中抗-TP初筛反应性标本11 05例,确证试验阳性标本555例,平均感染率为0.15%。献血者确认阳性中31~40岁年龄段最高(38.56%);不同地区、不同职业、不同文化程度阳性率比较均差异有统计学意义(均P<0.05)。结论:襄阳地区无偿献血者抗-TP阳性率处于较低水平,但梅毒对血液安全仍然存在威胁,今后工作中我站应结合该地区实际情况,加强对高危献血者在梅毒防治知识上的健康教育,对不同人群有针对性的开展无偿献血宣传,为本地区献血事业持续健康发展提供坚实保障。
Objective：To analyze of the test results and infection trends of the TP antibody in Xiangyang area for 5 years and provide a scientific basis for the recruitment strategy of blood donors and the selection of street screening methods,in order to ensure maximum blood safety.Method：The two different anti-TP enzyme-linked immune reagents were used to screen samples,TP-PA method was confirmed.The results were statistically analyzed byχ2-test.Result：360 711 doses of blood donors screening results showed that the 1 105 samples were antiTP antibody positive,555 samples were further confirmed by laboratory diagnosis.The TP infection rate was0.19%（555/360 711）.The positive rate of blood donors was the highest in the age of 31-40 years,up to38.56%.The differences in occupations,regions and cultures were satistically significant.Conclusion：Anti-TP positive rate was at a lower level in Xiangyang,but it still would be a threat to blood safety.In the future work,according to the actual situation,it should strengthen health education for high risk blood donors,make publicity for different groups of people,so as to provide solid guarantee for the sustainable and healthy development of blood donation in the region.
作者
郑艳梅
赵旻
汪慧
ZHENG Yanmei;ZHAO Min;WANG Hui(Xiangyang Blood Center, Xiangyang, 441021, China;Wuhan University Basic Medical School;Huazhong University of Science and Technology Tongji Medical College Affiliated to Wuhan Central Hospital Laboratory)
出处
《临床血液学杂志（输血与检验）》
CAS
2018年第3期429-432,共4页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
关键词
无偿献血者
梅毒
血液检测
blood donors
syphilis
blood detection
