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米力农对慢性充血性心力衰竭患者血清脑利钠肽的影响 被引量:2

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摘要 目的探讨米力农对慢性充血性心力衰竭(CHF)患者血清脑利钠肽(BNP)的影响。方法采用随机数字表法将112例CHF患者分为观察组和对照组,各56例。两组均接受常规治疗,观察组在此基础上接受静脉滴注米力农治疗,连续治疗2个疗程。于治疗前后对患者进行心功能及血清BNP检测。结果治疗前,两组左室舒张末期内径(LVIDD)、左心室射血分数(LVEF)和每搏输出量(SV)差异均无统计学意义(均P>0.05);治疗后,两组LVEF、LVIDD和SV均较治疗前显著改善(均P<0.05),且观察组优于对照组(均P<0.05)。治疗前,两组血清BNP水平差异无统计学意义(P>0.05);治疗后,观察组血清BNP水平低于对照组(P<0.05),BNP下降程度高于对照组(P<0.05)。两组均未见严重恶性心律失常、低血压等发生。结论正性肌力药米力农可降低CHF患者血清BNP水平,改善心功能,且安全性好。
作者 陈娟英
出处 《现代实用医学》 2018年第5期607-609,共3页 Modern Practical Medicine
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