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甲硝唑凝胶以及米诺环素治疗牙周炎的临床效果比较 被引量:2

Comparison of Clinical Effects of Metronidazole Gel and Minocycline in the Treatment of Periodontitis
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摘要 目的比较分析甲硝唑凝胶以及米诺环素两种药物治疗牙周炎患者的临床效果。方法选取2017年1—12月在我院进行诊治的76例牙周炎患者作为研究对象,将其随机分为两组。对照组使用甲硝唑凝胶治疗,观察组使用米诺环素软膏治疗。比较两组治疗前后的临床检测指标。结果观察组治疗有效率为92.11%,高于对照组的73.68%,差异具有统计学意义(P<0.05);两组治疗后的临床检查指标均明显改善,差异具有统计学意义(P<0.05),且观察组优于对照组,差异具有统计学意义(P<0.05)。结论米诺环素治疗牙周炎患者的临床效果优于甲硝唑凝胶,可以较为满意的控制炎性因子水平,改善临床症状。 Objective To compare the clinical effects of metronidazole gel and minocycline in the treatment of periodontitis. Methods 76 cases of periodontitis who were treated in our hospital from January to December 2017 were randomly divided into two groups. The control group was treated with metronidazole gel, and the observation group was treated with minocycline ointment. The clinical examination indexes were compared between the two groups before and after treatment. ResultsThe effective rate of treatment in the observation group was 92.11%, which was significantly higher than that of the control group 73.68%, the difference was statistically significant(P〈0.05). The clinical examination indexes of the two groups were obviously improved, the difference was statistically significant(P〈0.05), and the observation group was obviously superior to the control group, the difference was statistically significant(P〈0.05). Conclusion The clinical effect of minocycline in the treatment of periodontitis is significantly better than that of metronidazole gel. It can control the level of inflammatory factors satisfactorily and improve the clinical symptoms.
作者 姑丽米日.依马木 王巧云 Gulimiri·Yimamu;WANG Qiaoyun(Department of Stomatology, The 474thHospital of the PLA, Urumqi Xinjiang 830000, Chin)
机构地区 解放军第
出处 《中国继续医学教育》 2018年第16期119-121,共3页 China Continuing Medical Education
关键词 甲硝唑凝胶 米诺环素 牙周炎 临床效果 炎性因子 临床症状 metronidazole gel minocycline periodontitis clinical effect inflammatory factors clinical symptoms
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