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胶体金法测定心肌肌钙蛋白Ⅰ的效果及其假阳性结果分析

Effects of colloidal gold assay on cardiac troponin Ⅰ and its false positive results
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摘要 目的分析胶体金法测定心肌肌钙蛋白Ⅰ(cTnI)的效果及其假阳性结果。方法选取120例急性心肌梗死患者为研究对象,均采用胶体金法进行心肌肌钙蛋白Ⅰ及其他心肌酶的测定。统计胶体金检测法的检测特性,如准确性、特异性及敏感性。结果应用胶体金检测法,120例心肌梗死患者N末端脑钠肽、cTnI含量分别为(1 789.2±217.4)ng/L、(0.26±0.03)μg/L。胶体金检测的准确性、敏感性、特异性分别为96.6%、86.2%、95.1%。结论胶体金测定法临床操作简便,检测速度快,心肌肌钙蛋白Ⅰ检测准确度较高。 Objective To investigate the effects of colloidal gold assay on cardiac troponin I and to analyze its false positive results. Methods A total of 120 patients with acute myocardial infarction were selected as the research subjects, and all the patients involved in the study were detected by colloi- dal gold assay for the cardiac troponin I and other myocardial enzymes. The characteristics of colloidal gold assay, such as accuracy, specificity and sensitivity were analyzed. Results Using the colloidal gold assay, the contents of NT-proBNP and cTnI in 120 patients with myocardial infarction were (1789.2± 217.4) ng/L and (0. 26 ± 0. 03 ) g/L respectively. The accuracy, sensitivity and specificity of colloidal gold detection were 96.6% , 86. 2% and 95.1% respectively. Conclusions Compared with other meth- ods, colloidal gold assay has high accuracy, and is easy to operate for the determination of cardiac tropo- nin I, which should be further popularized in clinical application.
作者 钟文晖 何荣锌 邓进取 田东平 Zhong Wenhui;He Rongxin;Deng Jinqu;Tian Dongping(The Second Chinese Medicine Hospital of Meizhou, Meizhou 514000, China)
出处 《临床医学》 CAS 2018年第6期12-13,16,共3页 Clinical Medicine
关键词 胶体金测定法 心肌肌钙蛋白514000 假阳性 Colloidal gold assay Cardiac troponin Ⅰ False positive
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