摘要
患儿女,5岁,左前臂丘疹3年余。皮肤科情况:左前臂屈侧可见呈横行线状分布的直径1~10mm大小红色丘疹,境界清楚,质地稍硬,表面光滑。皮损组织病理示:表皮大致正常,真皮全层及脂肪层浅层可见单一核细胞呈致密结节状浸润。免疫组织化学示:CD3、CD5、CD20、CD79a、Bcl-2部分阳性,CD10、CD21、Bcl-6、Cyclin D1阴性,Ki-67约20%阳性,免疫球蛋白轻链kappa、lamda阴性。Ig H、Igκ基因重排未见克隆性扩增峰。诊断:假性淋巴瘤。治疗:患者家属选择观察,1年后皮损部分消退。
A 5-year-old girl presented with rashes on her left forearm for more than 3 years. Dermatologic examination showed multiple red, dome-shaped papules of 1- 10mm in diameter with linear arrangement crossed the flexural lateral of left fore- arm. Histologie examination showed a normal epidermis and dense nodular infiltra- tions of mononuelear cells extending from dermis to subcutaneous tis- sue. Immunophenotypie studies showed mononuclear cells were partly positive for CD3, CD5, CD20, CD79a and Bcl-2, negative for CD10, CD21, Bel-6, CyclinD1, im- munoglobulin kappa light chain and immunoglobulin lamda light chain, Ki67 were a- bout 20% positive. Gene rearrangement of IgH and Igk were negative. A diagnosis of cutaneous pseudolymphoma was made. One year later, the skin lesions were partially regressed.
作者
江夏
王伟霞
张敏
JIANG Xia, WANG Weixia, ZHANG Min(Department of Dermatology＆Venereology, West China Hospital, Sichuan University, Chengdu 610041, China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2018年第4期429-431,共3页
The Chinese Journal of Dermatovenereology
关键词
假性淋巴瘤
皮肤
线状
Psudolymphoma
Cutaneous
Linear
