摘要
目的调查台州地区门诊患者淋球菌(NG)、解脲脲原体(UU)和沙眼衣原体(CT)感染状况,为临床诊断治疗提供依据。方法采用实时荧光核酸恒温扩增技术(SAT)对2016年台州市中心医院诊治的疑似NUC门诊患者进行NG、UU和CT核酸检测,并对其检测结果进行统计学分析。结果 1 365例疑似NG门诊患者中,检出阳性患者127例,阳性率为9.30%;1 661例疑似UU门诊患者中,检出阳性患者676例,阳性率为40.70%;3 799例疑似CT门诊患者中,检出阳性患者417例,阳性率为10.98%。各年龄段阳性率不同,20岁~40岁阳性患者最多。混合感染中以UU+CT感染常见。结论台州地区门诊患者NUC感染率各不相同,其中UU感染率最高。男性易感染NG和CT,女性易感染UU。SAT技术在NG、UU和CT核酸检测中具有灵敏度高,方便快捷等优点,值得临床应用。
Objective In order to provide basis for clinical diagnosis and treatment,we investigated the infection status of Neisseria gonorrhoeae（ NG）,Ureaplasma urealyticum（ UU） and Chlamydia trachomatis（ CT） in outpatients of Taizhou area. Methods NG,UU and CT nucleic acid were tested by real-time fluorescent nucleic acid isothermal amplification technology of our hospital in 2016. Then we statistically analyze the test results of them. Results 127 cases were positive in 1 365 suspected NG outpatients,with the positive rate of 9. 30%; 676 cases were positive in 1 661 suspected UU outpatients,with the positive rate of 40. 70%; 417 cases were positive in 3 799 suspected CT outpatients,with the positive rate of 10. 98%. All age groups had different positive rates,and the most positive patients were in 20-40 years old. UU ＋ CT infection was the most common one.Conclusion The outpatients in Taizhou had different positive rates of NUC,UU infection rate is the highest,followed by CT,NG. Male are more susceptible to NG and CT,but female are more susceptible to UU. SAT is high sensitive,convenient and rapid in the nucleic acid detection of NG,UU and CT,which is worthy of clinical application.
作者
许美芬
梁玲芝
徐友文
吴晓宇
陈贤君
XU Mei- fen, LIANG Ling- zhi, XU You- wen, WU Xiao- yu, CHEN Xian- jun(Clinical Laboratory, Taizhou Central Hospital, Taizhou, Zhejiang 318000, Chin)
出处
《中国卫生检验杂志》
CAS
2018年第4期419-421,共3页
Chinese Journal of Health Laboratory Technology
基金
台州市科技计划项目(1601KY19)
台州恩泽医疗中心(集团)科研基金项目(15EZD1)
关键词
淋球菌
解脲脲原体
沙眼衣原体
实时荧光核酸恒温扩增技术
Neisseria gonorrhoeae
Ureaplasma urealyticum
Chlamydia trachomatis
Real -time fluorescent nucleic acid isothermal amplification technology
