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成纤维细胞生长因子2、18与软骨细胞增殖的研究进展 被引量:2

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摘要 软骨组织工程主要通过对软骨种子细胞、软骨支架、细胞因子的研究,来解决修复关节软骨损伤、退变这一难题。多肽生长因子如转化生长因子(TGF)-β、骨形态发生蛋白(BMP)、甲状旁腺相关蛋白(PTHrP)、成纤维细胞生长因子(FGF)等对关节软骨的内环境稳态及修复起十分重要作用。经典的FGF信号通路包含18个信号蛋白与4个酪氨酸激酶分子蛋白受体(FGFRs)。
出处 《中国老年学杂志》 CAS 北大核心 2018年第5期1272-1274,共3页 Chinese Journal of Gerontology
基金 湖北省卫生计生西医类重点资助项目(No.WJ2015MA025) 宜昌市医疗卫生科研项目(No.A15301-09)
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