摘要
目的研究综合保胎治疗对复发性流产妊娠结局效果分析。方法选取256例复发性流产患者按整群抽样法分为对照组和观察组，各128例，两组均给予常规保胎治疗，观察组在此基础上给予综合保胎治疗，观察两组妊娠结局、抗心磷脂抗体清除有效率和妊娠期并发症。结果观察组的妊娠成功率为82．03％，高于对照组的63．28％，流产率为17．97％，低于对照组的36．72％，差异均有统计学意义（均P〈0．05）；观察组抗心磷脂抗体清除率为69．53％，高于对照组的44．53％（P〈0．05）；观察组妊娠期合并高血压（2．34％）、合并胎膜早破（14．06％）及总并发症的发生率（23．44％）均低于对照组（分别为8．57％、29．69％、46．88％）（均P〈0．05），两组胎儿宫内生长受限、羊水异常、胎盘前置、糖尿病的发生率比较，差异无统计学意义（P〉0．05）。结论综合保胎治疗在复发性流产中临床疗效显著，可以有效减少妊娠期合并高血压及胎膜早破的发生率，有效清除抗心磷脂抗体，提高活产率，减少流产及早产的发生，应用价值高。
Objective To study the effect of comprehensive tocolytic therapy on the pregnancy outcomes of recurrent spontaneous abortion. Methods 256 recurrent spontaneous abortion patients were divided into a control group （ 128 cases ） and an observation group （ 128 cases ） using cluster sampling method. Both groups were treated with conventional tocolytic therapy; besides, the observation group was given comprehensive tocolytic therapy. The pregnancy outcomes, effective rates of clearance of anticardiolipin antibody and pregnancy complications in the two groups were observed and compared. Results The pregnancy success rate was 82.03% in the observation group and 63.28% in the control group, with a statistical differences （ P 〈 0.05 ） . The abortion rate was 17.97% in the observation group and 36.72% in the control group, with a statistical difference （ P 〈 0.05 ）. The effective rate of clearance of anticardiolipin antibody was 69.53% in the observation group and 44.53% in the control group （ P 〈 0.05 ） . The incidences of pregnancy associated with hypertension and pregnancy associated with premature rupture of membrane and the total incidence of complications were 2.34%, 14.06%, and 23.44% in the observation group and were 8.57%, 29.69%, and 46.88% in the control group （ all P 〈 0.05 ） . There were no statistical differences in the incidences of fetal growth restriction, abnormal amniotic fluid, placenta previa, and diabetes between the two groups （ all P 〉 0.05 ） . Conclusion Comprehensive tocolytic therapy has significant effect and high application value on recurrent spontaneous abortion and can effectively reduce the incidences of pregnancy complicated with hypertension and premature rupture of membranes, eliminate anticardiolipin antibody, improve the live birth rate, and reduce the incidence of abortion and premature delivery.
出处
《国际医药卫生导报》
2018年第2期208-210,共3页
International Medicine and Health Guidance News
关键词
综合保胎治疗
复发性流产
妊娠
Comprehensive tocolytic therapy
Recurrent spontaneous abortion
Pregnancy
